PregnancyMagnetic Resonance ImagingClinical CompetenceSurveys and QuestionnairesQualitative ResearchInterviews as TopicLength of StayIntensive Care Units, NeonatalNeuroma, AcousticCooperative BehaviorPublic HealthHealth WorkforcePhysiciansEnglandWorkplace
Dr. Locke studies a variety of topics within healthcare, with a particular interest in how healthcare professionals are trained and retained. He examines factors influencing career choices for roles like physiotherapists and podiatrists in England, striving to improve recruitment strategies to enhance patient care. Additionally, he investigates treatments for conditions such as opioid use disorder, assessing how these treatments can be personalized for better patient outcomes. His work also includes evaluating the impacts of social policies on maternal and infant health and understanding the role of parental support in high-stress medical environments like Neonatal Intensive Care Units (NICUs).
Key findings
In a study on opioid use disorder, 28.5% of participants were completely drug-free after 24 weeks of treatment with extended-release buprenorphine.
Research on vestibular schwannomas found that about 51% of growing tumors stopped growing within an average of four years without treatment.
22 out of 28 programs aimed at reducing stress in student nurses showed positive results, with a focus on coping skills proving effective in 74% of cases.
State-level policies like tax credits and paid parental leave were linked to improved perinatal health outcomes, suggesting that supportive policies can reduce issues such as preterm births and infant deaths.
Only 2.6 out of 5 was the average stress level reported by parents of NICU babies at discharge, revealing that even protective factors may not significantly reduce stress during their child's hospitalization.
Frequently asked questions
Does Dr. Locke study career choices in healthcare?
Yes, Dr. Locke examines how students choose careers in allied health professions and what influences those decisions.
What treatment has Dr. Locke researched for opioid use disorder?
He has studied the effectiveness of extended-release buprenorphine as a treatment for opioid use disorder.
Is Dr. Locke's work relevant to parents of newborns in intensive care?
Absolutely, his research includes examining the stress levels of parents with babies in Neonatal Intensive Care Units (NICUs) and the factors that influence their experiences.
How does social policy impact health outcomes according to Dr. Locke?
His work indicates that certain social policies, like paid parental leave, can lead to better health outcomes for mothers and infants.
What is Dr. Locke's focus regarding vestibular schwannomas?
He investigates how and when to monitor patients with vestibular schwannomas after treatment, including the growth patterns of these tumors.
Publications in plain English
Sources of influence for choosing an operating department practitioner career: Findings from a questionnaire among students in England.
2025
Journal of perioperative practice
Wallis L, Palmer M, Locke R, Faulkner J, Lowes H +1 more
Plain English This study looked at what encourages students in England to become operating department practitioners, who are key members of surgical teams. Out of 150 students surveyed, personal connections like role models were the biggest influence, while school resources had little impact. Understanding and experiencing the job firsthand were crucial for keeping students engaged in the program and pursuing this career path.
Who this helps: This helps students considering a career in healthcare and educators seeking to improve recruitment.
Extended-release buprenorphine treatment for opioid use disorder: A mixed-methods study of response and experience.
2025
Addiction (Abingdon, England)
Lowry N, McKechnie A, Day E, Gilvarry E, Cowden F +9 more
Plain English This study looked at how well a treatment called extended-release buprenorphine (BUP-XR) worked for people with opioid use disorder over 24 weeks. They found that 28.5% of participants stayed completely drug-free, while another 28.5% managed to stop using opioids but had cravings and sometimes turned to other drugs for relief. The research showed that people reacted differently to the treatment, indicating the importance of customizing care to fit each individual's situation.
Who this helps: This helps patients with opioid use disorder and their healthcare providers.
What drives career choice in allied health professions in England? Insights from a national questionnaire.
2025
BMC health services research
Wallis L, Palmer M, Locke R, Faulkner J, Biddle C +1 more
Plain English This study looked at what influences people in England to choose careers as Allied Health Professionals (AHPs), such as physiotherapists and radiographers. Researchers surveyed 1,318 students and found that many decide on their careers either after having another job (32.5%) or while in college (26.6%). Understanding these factors can help create better recruitment strategies to ensure there are enough AHPs to meet the needs of the healthcare system.
Who this helps: Patients in need of healthcare services will benefit from having more AHPs available.
Furthering understanding of the scope and variation of alcohol and drug harms to others: Using qualitative discussion groups to inform survey development.
2024
International journal of alcohol and drug research
Karriker-Jaffe KJ, Munroe C, McDonough M, Lui CK, Krug Mangipudi D +5 more
Plain English This study explored how alcohol and drug use negatively affects the families and friends of those who use these substances. By conducting discussion groups in five U.S. cities, researchers found that these harms can lead to long-lasting emotional stress and may be worsened by negative interactions with legal and social services. The insights gained from participants helped refine a national survey to better capture the range of experiences related to these harms.
Who this helps: This helps patients, their families, and healthcare providers understand the broader impacts of substance use.
Can Mozart Improve Weight Gain and Development of Feeding Skills in Premature Infants? A Randomized Trial.
2023
American journal of perinatology
Lafferty MA, Mackley A, Green P, Ottenthal D, Locke R +1 more
Plain English This study looked at whether listening to Mozart's music could help very premature infants (those born between 28 and 31 weeks of pregnancy) gain weight and improve their feeding skills. Researchers played Mozart's music for 14 days to some infants, while others did not hear the music. The results showed no significant difference between the two groups in how quickly they regained their birth weight or how well they learned to feed orally.
Who this helps: This research provides insights for doctors and caregivers of premature infants, helping them understand that Mozart's music may not significantly enhance weight gain or feeding skills in these babies.
How many growing vestibular schwannomas tend to stop growing without any treatment?
2023
The Journal of laryngology and otology
Donghun K, Crowther JA, Taylor WAS, Locke R, Kontorinis G
Plain English This study looked at how many patients with growing vestibular schwannomas, a type of tumor in the head, stop their growth without treatment. Out of 735 patients, about 39% had tumors that were growing, and of those, about 51% stopped growing after an average of four years. This finding is important because it helps doctors understand that a significant number of these tumors may stabilize on their own, potentially reducing the need for aggressive treatment.
Who this helps: This benefits patients with vestibular schwannomas by providing insight into their condition and management options.
The impact of kangaroo mother care on work of breathing and oxygen saturation in very low birth weight infants with respiratory insufficiency.
2023
Journal of neonatal-perinatal medicine
Gable M, Shaffer TH, Locke R, Mackley A, Kovatis KZ
Plain English This study looked at the effects of kangaroo mother care (KMC)—where a baby lies skin-to-skin on their mother’s chest—on very low birth weight infants who were having trouble breathing. Researchers measured how hard the babies had to work to breathe and their oxygen levels while they received either KMC or standard care. They found no significant difference in breathing effort or oxygen levels between the two methods, suggesting that KMC is safe and well-tolerated for these infants.
Who this helps: This benefits infants with low birth weight and their mothers.
Building a Sustainable Governmental Public Health Workforce: A Look at the Millennial Generation.
2022
Journal of public health management and practice : JPHMP
Locke R, Gambatese M, Sellers K, Corcoran E, Castrucci BC
Plain English This study looked at the attitudes and job satisfaction of millennials (ages 21-36) working in public health compared to older generations. It found that millennials made up 22% of this workforce in 2017 and, like their colleagues from Generation X and the baby boomers, were generally satisfied with their jobs. However, millennials felt less fully engaged in their work, even though they valued respect from supervisors and opportunities for innovation. This research is important because it helps public health agencies understand how to attract and keep young professionals in the field.
Who this helps: This benefits public health agencies trying to recruit and retain younger workers.
Attracting New Talent to the Governmental Public Health Workforce: Strategies for Improved Recruitment of Public Health Graduates.
2022
Journal of public health management and practice : JPHMP
Locke R, McGinty M, Guerrero Ramirez G, Sellers K
Plain English This study looked at why many public health graduates aren't choosing to work for government public health agencies, despite wanting meaningful jobs that help communities. Researchers held focus groups with 33 public health students from three universities and found that students see government jobs as bureaucratic and lacking resources, making it hard to find job opportunities. To attract more graduates to these roles, GPH agencies need to improve their recruitment methods and highlight the fulfilling aspects of the work better.
Who this helps: This benefits public health agencies looking to recruit new talent and improve community health.
The effectiveness of interventions and behaviour change techniques to reduce stress in student nurses: A systematic review.
2022
Nurse education today
Petley B, Husted M, Lees A, Locke R
Plain English This study looked at various programs designed to help student nurses reduce their stress levels. Out of 28 programs examined, 22 showed positive results, with 74% of those focusing on coping skills working effectively. This is important because high stress in student nurses can lead to health issues and dropping out of their programs.
Who this helps: This research benefits student nurses by providing effective strategies to manage their stress.
Plain English This study examined how advanced clinical practitioners (ACPs) are assessed in emergency healthcare settings in England to ensure they are well-trained and capable. Researchers looked at two hospitals, finding that one had a clear assessment process while the other was in the process of improving its evaluation methods. The findings highlight the importance of effective assessment systems for the future success of ACPs, ultimately supporting better patient care.
Who this helps: This helps patients by ensuring that ACPs are properly trained and qualified to provide high-quality healthcare.
State-Level Social and Economic Policies and Their Association With Perinatal and Infant Outcomes.
2022
The Milbank quarterly
Webster JL, Paul D, Purtle J, Locke R, Goldstein ND
Plain English This study looked at how different state-level social and economic policies, like tax credits, paid parental leave, minimum wage laws, and tobacco taxes, affect the health of mothers and infants. The researchers found that most of these policies are linked to better health outcomes for pregnant women and newborns. For instance, states with tax credit laws and paid parental leave saw improved results in perinatal health, highlighting that such policies can make a real difference in reducing issues like preterm births and infant deaths.
Who this helps: This helps patients, especially mothers and infants, by promoting better health outcomes through supportive state policies.
Motivations, sources of influence and barriers to being a podiatrist: a national questionnaire of student views.
2022
Journal of foot and ankle research
Wallis L, Faulkner J, Locke R, Harden B, Cowley EE
Plain English This study looked at why students choose to become podiatrists and the challenges they face. Researchers surveyed 115 podiatry students in England and found that most were motivated by a desire to help others, with personal experiences influencing their decisions. They also noted that a lack of understanding about what podiatrists do is a significant barrier to entering the profession, and improvements in education and marketing could attract more students to podiatry courses.
Who this helps: This benefits future podiatrists and ultimately improves foot health care for patients.
Breastfeeding and Formula Selection in Neonatal Abstinence Syndrome.
2021
American journal of perinatology
Lembeck AL, Tuttle D, Locke R, Lawler L, Jimenez P +2 more
Plain English This study looked at the effects of different feeding methods on infants with Neonatal Abstinence Syndrome (NAS), a condition caused by withdrawal from substances. Researchers found that breastfeeding helped reduce the length of hospital stays by about 7 to 10 days and the time these babies needed medication by about 7 days, while there was no difference in outcomes between standard formula and low lactose formula. The findings highlight the importance of breastfeeding for improving health outcomes in NAS infants, even though it may lead to more weight loss compared to formula-fed babies.
Who this helps: This helps mothers of NAS infants and healthcare providers.
Imaging Post Stereotactic Radiosurgery for Vestibular Schwannomas-When Should We Scan?
2021
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Ton T, Sheldon A, Tikka T, Locke R, Crowther JA +1 more
Plain English This study looked at the best timing for MRI scans after patients with vestibular schwannomas, a type of brain tumor, received stereotactic radiosurgery (SRS) treatment. Researchers analyzed data from 42 patients and found that tumors initially grew slightly after treatment but then showed a significant decrease in growth rate over time—dropping from an average of 0.26 mm per month before treatment to just 0.05 mm per month within a year after treatment. The findings suggest that scanning too soon after SRS (within one year) is generally unhelpful, and monitoring growth rates is a better way to track treatment response.
Who this helps: Patients with vestibular schwannomas and their doctors.
Parental protective factors and stress in NICU mothers and fathers.
2021
Journal of perinatology : official journal of the California Perinatal Association
Ivashchuk A, Guillen U, Mackley A, Locke R, Sturtz W
Plain English This study looked at how certain protective factors in parents affect their stress levels when their babies are admitted to a Neonatal Intensive Care Unit (NICU). Researchers found that parents' stress levels at the time of admission were around 2.8 out of 5 and dropped slightly to 2.6 before discharge, while their protective factors measured high. However, the study revealed that these protective factors did not significantly reduce parental stress during their NICU experience.
Who this helps: This helps NICU parents by highlighting the challenges they face and the need for effective support systems.
A literature review of interventions to reduce stress in doctors.
2020
Perspectives in public health
Locke R, Lees A
Plain English This study reviewed various programs designed to help doctors manage stress. It found that 31 studies, involving a total of 1,356 doctors, showed that approaches like mindfulness, solution-focused coping, and reflective group discussions can effectively reduce stress levels. This is important because it provides a roadmap for creating educational programs that better support doctors' mental health, which can improve their well-being and patient care.
Who this helps: This helps doctors by equipping them with effective stress management techniques.
Musculoskeletal (MSK) practitioners in primary care: an evaluation of a MSK core capabilities framework and review process.
2020
Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors
Locke R, Wilkinson E, Collier R, Harden B
Plain English This study looked at how well a new framework works for evaluating the skills of musculoskeletal (MSK) physiotherapists in primary care settings. Twenty-two MSK practitioners shared their experiences, revealing that the framework is useful for quality assurance and career development, but it also needs some improvements to be put into practice effectively. This is important because it helps ensure MSK practitioners are qualified and well-supported in their roles, which can lead to better patient care.
Who this helps: This benefits patients and MSK physiotherapists by improving the quality of care provided in primary care settings.
How Do Contexts Affect Physicians' Clinical Reasoning? A Narrative Review.
2020
MedEdPublish (2016)
Mason A, Locke R, Lusznat RM, Coles C, Masding MG
Plain English This study looked at how different situations influence doctors' ability to think critically and make decisions about patient care. It found that a doctor's reasoning can be affected by three main factors: the patient's individual circumstances, the doctor's own background and emotions, and the environmental conditions they are working in, like time constraints or unfamiliar settings. Understanding these influences is important because it can help improve medical training and patient outcomes.
Who this helps: This helps doctors and healthcare teams in providing better patient care.
Feasibility and utility of enhanced sleep management on in-patient psychiatry wards.
2020
BJPsych bulletin
Novak C, Packer E, Paterson A, Roshi A, Locke R +3 more
Plain English This study looked at ways to improve sleep for patients in psychiatric wards, as poor sleep can make mental health issues worse. The researchers implemented changes such as reducing frequent checks on patients and screening for sleep disorders. They found that 50% of patients were able to sleep uninterrupted through the night, and there were no serious problems from these changes, along with a decrease in sleep medication use.
Who this helps: This benefits patients in psychiatric care by promoting better sleep and overall mental health.
The development of clinical thinking in trainee physicians: the educator perspective.
2020
BMC medical education
Locke R, Mason A, Coles C, Lusznat RM, Masding MG
Plain English This research studied how doctors in training, known as trainee physicians, learn to think critically in medical situations. Educators interviewed for the study shared that having a supportive learning environment, being closely present with trainees, and monitoring their progress helped improve their clinical thinking skills. The findings highlight the role of teamwork and feedback in medical education, suggesting that with the right support, trainee physicians can become better prepared for their roles.
Who this helps: This benefits trainee physicians and their educators.
State and Local Government Expenditures and Infant Mortality in the United States.
2020
Pediatrics
Goldstein ND, Palumbo AJ, Bellamy SL, Purtle J, Locke R
Plain English This study looked at how state and local government spending on services such as education and social programs affects infant mortality rates (IMRs) in the U.S. Researchers found that increasing spending on social services by $0.73 per person was linked to a reduction of 0.02 deaths per 1,000 live births, while a $0.30 increase in environmental spending led to a decrease of 0.03 deaths per 1,000 live births. The greatest benefits were seen among infants born to mothers under 20, showing that investing in these non-health care services can lower death rates for vulnerable populations.
Who this helps: This benefits infants, especially those born to young mothers and in high-risk communities.
Co-production of "nature walks for wellbeing" public health intervention for people with severe mental illness: use of theory and practical know-how.
2020
BMC public health
Hubbard G, Thompson CW, Locke R, Jenkins D, Munoz SA +4 more
Plain English This study developed a program called "nature walks for wellbeing" aimed at helping people with severe mental health issues improve their mental and physical health. The research found that people with these conditions often lead sedentary lives, which can increase their risk of serious health problems, and that nature walks could be a practical way to encourage them to be more active and socially connected. The program will last for 12 weeks and includes a booklet and regular text messages, allowing participants to engage with nature and enhance their well-being at a low cost.
Who this helps: This benefits patients with severe mental illness by providing a supportive and active way to improve their health.
Doctors with Asperger's: the impact of a diagnosis.
2019
The clinical teacher
Price S, Lusznat R, Mann R, Locke R
Plain English This study looked at how a diagnosis of Asperger syndrome (AS) affects medical trainees. It found that while having AS can help these doctors understand personal challenges, it can also lead to stigma and bias. Overall, recognizing AS traits can help create better support for these trainees and improve their work experience.
Who this helps: This helps medical trainees with Asperger syndrome and the educators who support them.
Outcome Differences in Neonates Exposed In-Utero to Opioids Managed in the NICU Versus Pediatric Floor.
2019
Journal of addiction medicine
Lembeck AL, Tuttle D, Locke R, Lawler L, Jimenez P +2 more
Plain English This study looked at the differences in how long infants with neonatal abstinence syndrome (NAS)—a condition caused by opioid exposure in the womb—stayed in the hospital and how long they were treated, depending on whether they were cared for in the neonatal intensive care unit (NICU) or a regular pediatric floor. The researchers found that infants in the NICU stayed an average of 27.1 days and received treatment for 18 days, while those on the pediatric floor stayed only 14.2 days and were treated for 9 days. This is important because caring for these infants outside of the NICU can lead to shorter hospital stays and lower healthcare costs.
Who this helps: This benefits families of infants with NAS and healthcare providers looking for more efficient care options.
Unleashing the Creativity and Innovation of Our Greatest Resource-The Governmental Public Health Workforce.
2019
Journal of public health management and practice : JPHMP
Locke R, Castrucci BC, Gambatese M, Sellers K, Fraser M
Plain English This study looked at how well government public health agencies recognize and reward creativity and innovation among their employees. It found that less than half (43%) of public health workers feel appreciated for their creative efforts, but those who do report higher job satisfaction and a better workplace environment. This is important because fostering a creative culture could lead to better problem-solving in public health and happier, more motivated employees.
Who this helps: This helps public health workers and organizations looking to improve their workforce and services.
Cochlear patency following translabyrinthine vestibular schwannoma resection: implications for hearing rehabilitation.
2019
The Journal of laryngology and otology
Carswell V, Crowther JA, Locke R, Taylor W, Kontorinis G
Plain English This study looked at how the cochlea, a part of the ear essential for hearing, is affected after removing a tumor called a vestibular schwannoma. Researchers found that 75% of patients had a clear cochlea at six months post-surgery, but this number dropped to 38.5% after one year, meaning more patients experienced blockages over time. This information is important because it suggests that the best time to consider cochlear implants, if needed, is within the first six months after the surgery to maximize chances of success.
Who this helps: This helps patients who may need cochlear implants after tumor removal.
Benefits of pre-labyrinthectomy intratympanic gentamicin: contralateral vestibular responses.
2019
The Journal of laryngology and otology
Amiraraghi N, Gaggini M, Crowther JA, Locke R, Taylor W +1 more
Plain English This study looked at how an injection of gentamicin (an antibiotic) before surgery affects recovery in patients who have surgery for a type of tumor called vestibular schwannoma. The findings showed that patients who received the gentamicin injection had a shorter hospital stay of about 6.75 days compared to 9.5 days for those who didn't receive it. Also, the gentamicin group had normal balance responses in the ear not affected by the surgery, while the other group did not.
Who this helps: This benefits patients undergoing vestibular schwannoma surgery by potentially leading to quicker recoveries.
Differences in Efficiencies Between ABS and RDD Samples by Mode of Data Collection.
2019
Survey practice
Pierannunzi C, Gamble S, Locke R, Freedner N, Town M
Plain English This study compared two ways of gathering survey responses—address-based samples (ABS) and random digit dialing (RDD)—to see which method was more efficient. It found that while ABS matched more addresses with phone numbers, RDD was cheaper and more accurate in connecting participants. Specifically, costs per completed interview were lower for RDD, making it a more effective option for gathering survey data.
Who this helps: This benefits researchers looking to conduct surveys more efficiently and cost-effectively.
The Joint Effects of Antenatal Steroids and Gestational Age on Improved Outcomes in Neonates.
2018
Maternal and child health journal
Goldstein ND, Kenaley KM, Locke R, Paul DA
Plain English This study looked at how antenatal steroids, given to pregnant women at risk of preterm birth, help improve the health of newborns, especially based on how far along the pregnancy is. Researchers found that among over 5,300 infants, 6% died, 5% had severe brain bleeding, and 10% experienced serious lung issues. The results showed that antenatal steroids significantly reduced the risk of death and severe lung problems, and for each week of increased gestational age, the protection became even stronger, cutting the incidence of these issues by 13%.
Who this helps: This benefits preterm infants and their mothers.
Vascular placental pathology and the relationship between hypertensive disorders of pregnancy and neonatal outcomes in very low birth weight infants.
2018
Journal of perinatology : official journal of the California Perinatal Association
Strouss L, Goldstein ND, Locke R, Paul DA
Plain English This study looked at how problems with the placenta’s blood vessels affect very low birth weight infants when their mothers have high blood pressure during pregnancy. Researchers found that babies whose mothers had both hypertension and placental issues had a significantly higher risk of developing lung problems, with a risk more than five times greater compared to babies whose mothers had just hypertension (5.23 times higher). This matters because it highlights the serious risks for newborns when both high blood pressure and placental issues occur together, which could guide better monitoring and care for these vulnerable infants.
Who this helps: This helps doctors and healthcare providers caring for pregnant women and their newborns.
Impact of endotracheal tube biofilm and respiratory secretions on airway resistance and mechanics of breathing in a neonatal lung model.
2018
Journal of applied physiology (Bethesda, Md. : 1985)
Kenaley KM, Blackson T, Boylan L, Ciarlo J, Antunes M +2 more
Plain English This study looked at how biofilm—a slimy layer of bacteria—forms on endotracheal tubes (ETTs) used in preterm infants and how it affects breathing. Researchers compared ETTs used on ventilated babies to new, unused tubes. They found that the used tubes had almost 20 cmH2O·sec more resistance than the control tubes, but only one out of 27 tests showed that biofilm really impacted breathing significantly. This means that for most infants, biofilm isn't a major problem when they breathe through these tubes.
Who this helps: This helps doctors and healthcare providers caring for preterm infants.
Spontaneous Vestibular Schwannoma Regression: A Case-Control Study.
2018
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Tikka T, Yiannakis CP, Stapleton E, Locke R, Crowther JA +2 more
Plain English This study looked at 540 patients with vestibular schwannomas (VS), a type of tumor affecting the auditory nerve, to understand why some tumors shrink on their own. It found that 5.2% of these tumors, or 28 patients, showed spontaneous regression, with an average size reduction of about 4mm (25.7% smaller), and most of these regressing tumors were located farther from a certain brain area compared to those that were growing. Understanding these patterns can help doctors better advise patients on what to expect from their tumors.
Who this helps: This helps patients with vestibular schwannomas and their doctors.
The experience and professional development of medical appraisers.
2018
Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors
Locke R, Bell J, Scallan S, Ozguler B, Caesar S
Plain English This study looked at how General Practitioner (GP) appraisers felt while assessing new colleagues in Jersey, a setting that was unfamiliar to them. Researchers conducted interviews with nine appraisers and found that these appraisers experienced culture shock and felt like beginners at first, needing to invest extra effort to build relationships. By their second round of evaluations, they recognized the value of appraisals in improving their professional skills. This research highlights that offering varied appraisal activities in new environments can support the professional growth of appraisers, which is important for ongoing development in healthcare around the world.
Who this helps: This helps doctors and GP appraisers.
Association between exhaled carbon monoxide and asthma outcomes in Peruvian children.
2018
Respiratory medicine
Pereira AA, Pollard SL, Locke R, Romero K, Lima JJ +3 more
Plain English Researchers in Lima, Peru studied the levels of exhaled carbon monoxide (eCO) in children with asthma compared to healthy children. They found that children with asthma had an average eCO level that was 0.56 parts per million higher, and those with higher eCO levels were more likely to have poorly controlled asthma: for instance, children in the highest eCO group were about 3.7 times more likely to have uncontrolled asthma than those in the lowest group. This matters because it shows that measuring eCO could be a simple and low-cost way to monitor asthma severity, especially in places with limited resources.
Who this helps: This helps patients with asthma and their doctors in low-resource areas.
Plain English This study looked at how dyslexia affects doctors and what support they need to thrive in their jobs. Researchers spoke with 14 doctors who have dyslexia and found that many of them come up with personal strategies to cope but often don't tell their employers about their condition. They identified that supportive work environments could help doctors perform better, and educators need to foster understanding and comfort for these doctors to disclose their dyslexia.
Who this helps: This helps doctors with dyslexia and the educators who train them.
Response to Comment on "Neutrophil to Lymphocyte Ratio as a Predictive Marker of Vestibular Schwannoma Growth".
2017
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Delayed Vestibular Schwannoma Regrowth Following Shrinkage After Stereotactic Radiosurgery: Implication for Life-Long Surveillance.
2017
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Stapleton E, Crowther JA, Locke R, Kontorinis G
Plain English This study looked at how vestibular schwannomas, a type of brain tumor, behave after being treated with a specific radiation therapy known as stereotactic radiosurgery. Out of 540 patients, two women whose tumors shrank after treatment experienced significant regrowth three years later, returning to their original size. This finding highlights the importance of ongoing monitoring for patients, as tumors can regrow even after a successful treatment response, suggesting that lifelong follow-up is necessary.
Who this helps: This helps patients with vestibular schwannomas and their doctors by emphasizing the need for continuous monitoring after treatment.
Time Series Analysis for Forecasting Hospital Census: Application to the Neonatal Intensive Care Unit.
2016
Applied clinical informatics
Capan M, Hoover S, Jackson EV, Paul D, Locke R
Plain English This study looked at how to improve predictions of how many babies would need care in a Neonatal Intensive Care Unit (NICU) by analyzing five years of daily patient data. The researchers developed new statistical models and found that their best models improved forecasting accuracy by about 36% compared to the traditional method of using last year's averages. This is important because better predictions can enhance patient safety and help hospitals allocate resources more effectively.
Who this helps: This helps hospital staff and administrators in planning and improving care for newborns.
Journal of special operations medicine : a peer reviewed journal for SOF medical professionals
Strohmayer J, Matthews I, Locke R
Plain English This study focused on schistosomiasis, a serious infection that people can catch from freshwater in tropical areas, particularly affecting military personnel who may travel to these regions. It highlighted the lack of information about this disease in soldiers compared to those living in areas where schistosomiasis is common and emphasized the need for better prevention and treatment strategies. The authors suggest important steps for diagnosis and management to reduce risks for military personnel.
Who this helps: This research benefits military personnel and healthcare providers responsible for their care.
Surveillance of ventricular septal defects in Delaware.
2016
Birth defects research. Part A, Clinical and molecular teratology
Acheson A, Vaidy A, Stomieroski K, Thompson DR, Maiden KM +5 more
Plain English Researchers studied the occurrence of ventricular septal defects (VSDs), which are heart defects present at birth, in Delaware. They found a high rate of 78.7 VSDs per 10,000 live births, significantly higher than rates in other states, which range from 1.6 to 70.0 per 10,000. This matters because understanding the prevalence helps in identifying areas for improved healthcare support and resources for affected families.
Who this helps: This helps patients and their families, healthcare providers, and policymakers.