DR. MARK GREGORY DESAUTEL, MD

SIOUX FALLS, SD

Research Active
Otolaryngology NPI registered 21+ years 6 publications 1972 – 2004 NPI: 1255338174
Case-Control StudiesRatsCells, CulturedBrainFibroblastsMitochondriaAgingAbdomenOxygen ConsumptionPelvisOsmolar ConcentrationCollagen Type ICytochromesMicrosomesCollagen Type III

Practice Location

1310 W 22ND ST
SIOUX FALLS, SD 57105-1501

Phone: (605) 328-8200

What does MARK DESAUTEL research?

Dr. Desautel studies stress urinary incontinence (SUI), a condition where physical activities like coughing or exercising lead to involuntary urine leakage. His work examines whether the body's collagen production, which is important for supporting pelvic floor muscles, is affected in women suffering from SUI. He aims to clarify misconceptions about the causes of SUI to aid in improving treatment options for affected women and to inform healthcare providers about this common condition.

Key findings

  • In a study of 14 women with SUI and 12 women without, there was no significant difference in collagen production, indicating that collagen levels are not responsible for SUI.
  • The findings suggest that reduced support experienced by women with SUI is not due to a lack of collagen synthesis, which shifts the focus of treatment options.

Frequently asked questions

Does Dr. Desautel study stress urinary incontinence?
Yes, he specifically researches the biological factors associated with stress urinary incontinence in women.
What treatments has Dr. Desautel researched?
His research helps inform treatment approaches for stress urinary incontinence, particularly focusing on underlying biological factors.
Is Dr. Desautel's work relevant to women experiencing urinary incontinence?
Yes, his findings directly relate to women experiencing stress urinary incontinence and aim to improve their treatment options.

Publications in plain English

Collagen synthesis is not altered in women with stress urinary incontinence.

2004

Neurourology and urodynamics

Chen Y, DeSautel M, Anderson A, Badlani G, Kushner L

Plain English
This study examined whether women with stress urinary incontinence (SUI) produce less collagen, which is believed to help support pelvic floor muscles. Researchers compared tissue samples from 14 women with SUI to those from 12 women without SUI, finding no significant difference in collagen production between the two groups. The results imply that the reduced support in women with SUI is not caused by a lack of collagen synthesis. Who this helps: This research benefits women experiencing stress urinary incontinence and healthcare providers looking for treatment options.

PubMed

Absence of effects of lead feedings and growth-retardation on mitochondrial and microsomal cytochromes in the developing brain.

1981

Toxicology and applied pharmacology

Holtzman D, Hsu JS, Desautel M

PubMed

Microsomal cytochromes in the immature and adult rat brain.

1980

Journal of neurochemistry

Holtzman D, Desautel M

PubMed

Effects of altered osmolality on respiration and morphology of mitochondria from the developing brain.

1979

Journal of neurochemistry

Holtzman D, Herman MM, Desautel M, Lewiston N

PubMed

Effects of osmolar changes on isolated mitochondria of brain and liver.

1978

Journal of neurochemistry

Holtzman D, Lewiston N, Herman MM, Desautel M, Brewer E +1 more

PubMed

Highly specific testicular adenosine-3', 5'-monophosphate phosphodiesterase associated with sexual maturation.

1972

Endocrinology

Monn E, Desautel M, Christiansen RO

PubMed

Frequent Co-Authors

D Holtzman M M Herman N Lewiston Yu Chen Ann Anderson Gopal Badlani Leslie Kushner J S Hsu E Brewer E Robin

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.