SARS-CoV-2COVID-19PregnancySurveys and QuestionnairesQualitative ResearchSeverity of Illness IndexFeasibility StudiesVaccinationCOVID-19 VaccinesSelf-ManagementPelvic Organ ProlapseFocus GroupsTranscutaneous Electric Nerve StimulationWhiteUrinary Incontinence
Dr. Myers studies a variety of health-related topics. He investigates how chronic diseases, such as kidney disease and certain types of cancer, develop and how they can be better managed. For example, he researches the impact of genetic changes in blood cancer patients on their treatment outcomes, and explores barriers that patients face in managing chronic kidney disease. Additionally, he examines the effects of traumatic birth experiences on parenting behaviors across different races. His work also delves into public health issues, such as the impact of air pollution on lung cancer rates and the risks children face related to firearm assaults in different time frames.
Key findings
In a study of 30 patients with blood cancer, those whose disease progressed had specific genetic changes, like the loss of TP53, helping to track disease progression.
Mothers who reported traumatic childbirth experiences showed a positive change in parenting behaviors with a notable score increase of 0.21, highlighting that trauma did not lead to negative caregiving behaviors.
In a systematic review on body mass index (BMI), the connection between BMI and prostate cancer risk was found to be unclear, indicating mixed results across studies.
A self-management program for kidney failure patients saw a 78% acceptance rate, with all participants reporting improved confidence and knowledge in managing their health.
Children were found to be 45% more likely to experience firearm injuries after 2 PM on school days, prompting calls for increased safety measures during afterschool hours.
Frequently asked questions
Does Dr. Myers study cancer?
Yes, he focuses on various types of cancer, including prostate cancer and blood cancers, particularly how they progress and the factors that influence their management.
What research has Dr. Myers done on maternal health?
He has studied the effects of traumatic childbirth experiences on maternal caregiving behaviors, finding that trauma may not necessarily lead to negative parenting outcomes.
Is Dr. Myers's work relevant for patients with chronic kidney disease?
Absolutely, he researches self-management challenges faced by kidney disease patients and has developed programs to help them better manage their health.
What insights has Dr. Myers provided on air pollution and health risks?
His research indicates that even without smoking, air pollution significantly contributes to lung cancer rates, emphasizing the need for improved air quality.
How does Dr. Myers's work address social issues like gun violence?
He has examined child firearm assault risks, uncovering critical timeframes when children are more vulnerable, signaling a need for increased safety measures in those hours.
Publications in plain English
Examining the Impact of the Syndemic on Black Birthing Individuals in the USA: a Systematic Review.
2026
Journal of racial and ethnic health disparities
Wisniewski K, Henry N, Flanagan AY, Popoola A, Weaver N +9 more
Plain English This study looked at how the COVID-19 pandemic and ongoing racism have negatively affected Black birthing individuals in the U.S. Researchers reviewed 50 studies and found significant issues such as medical mistrust, healthcare discrimination, and increased challenges related to housing, food, and family relationships. These findings highlight the urgent need for better support and targeted solutions to improve health outcomes for this group.
Who this helps: This helps Black birthing individuals and healthcare providers.
Hegarty KP, Kubota S, Cully M, McComas DJ, Christian ER +39 more
Plain English The IMAP Observatory studies how particles from the Sun interact with space to better understand the boundary of our solar system. It uses a spacecraft with ten special instruments to collect detailed data about solar wind and other particles. This research is important because it helps us learn more about the conditions in space that affect both our planet and the solar environment.
Who this helps: This helps scientists and researchers studying space weather and its effects on Earth.
Afterschool Child Firearm Assaults: A Quasi-Experimental Analysis.
2026
AJPM focus
Gause EL, McLone S, Myers D, Rick C, Rajan S +2 more
Plain English The study looked at the risk of children getting shot in New York City after school, specifically from 2006 to 2023. It found that the likelihood of firearm injury increased by 45% after 2 PM on school days, and there were about 2.5 more child firearm injuries right at that afterschool time, which is an increase of nearly 280% compared to the average on school days. This matters because it highlights a critical time when children are at greater risk, suggesting a need for safety measures during afterschool hours.
Who this helps: This helps children and their families by pointing out the need for better safety during afterschool times.
Feasibility and Acceptability of a Co-Designed Self-Management Programme for People Living With Kidney Failure.
2026
Journal of renal care
Lunardi LE, Leu RKL, Bastin R, Bennett PN, Donnelly F +12 more
Plain English This study looked at how a self-management program for people with kidney failure, designed with input from patients, could help them take control of their health before starting dialysis. Out of 40 patients invited, 31 joined the program, showing a high acceptance rate of 78%. Participants felt better educated and more confident in managing their health, with 100% of those who completed the program sticking with it.
Who this helps: This benefits patients with kidney failure who are not yet on dialysis.
Air pollution and lung cancer: an investigation of county-level residual incidence rates with smoking eliminated.
2026
Environmental health : a global access science source
Myers D, Mainali S, Afrin S, Kriebel D
Plain English This study looked at how air pollution affects lung cancer rates after removing smoking as a factor. Researchers found that even if smoking were completely eliminated, some counties would still have high lung cancer rates due to air pollution, with pollutants like PM (particulate matter), diesel exhaust, benzene, and radon contributing significantly. For example, specific pollutants like diesel exhaust and benzene were important in predicting which areas would still see high cancer rates after smoking's removal.
Who this helps: This research helps public health officials and cancer prevention advocates identify critical areas for air quality improvements to reduce lung cancer risk.
"Understanding Chronic Kidney Disease Self-Management Barriers and Facilitators: A Consumer-Led Qualitative Study".
2026
Journal of renal care
Lunardi LE, Matricciani LA, Le Leu RK, Bastin R, Myers D +9 more
Plain English The study examined the challenges and supports that patients with advanced chronic kidney disease face when trying to manage their illness. Researchers gathered insights from both patients and healthcare providers, finding six important themes, including the personal struggles patients experience and the need for better relationships with healthcare teams. Insights showed that patients often feel passive and discouraged, but positive attitudes and strong communication with doctors can improve their self-management.
Who this helps: This benefits patients with chronic kidney disease and their caregivers.
Body mass index and prostate cancer incidence: a comprehensive systematic review.
2026
Frontiers in oncology
Myers D, Chissum Lagos D, Zapata I, Hwang C
Plain English This research looked at whether body mass index (BMI) is linked to the risk of developing prostate cancer. The review found mixed results: while some studies indicated that a higher BMI might increase prostate cancer risk, others showed no clear connection, leading to an overall conclusion that the relationship between BMI and prostate cancer risk is unclear. Understanding this connection is important because prostate cancer is a major health concern for men, and clearer insights could help improve prevention strategies.
Who this helps: This helps patients and healthcare providers by better informing prostate cancer risk factors and prevention strategies.
Traumatic birth experiences and maternal caregiving behaviors and attitudes in black and white women.
2026
Archives of women's mental health
Kornfield SL, Henry NM, Waller R, White L, Gur R +4 more
Plain English This study looked at the effects of traumatic birth experiences on how mothers care for and bond with their babies, focusing on both Black and White women. Researchers found that mothers who reported more trauma during childbirth tended to show better positive parenting behaviors, with a notable score increase of 0.21, although this didn’t persist at 12 weeks or 24 months postpartum. The findings highlight that childbirth trauma does not necessarily lead to negative caregiving behaviors, and race did not change this relationship.
Who this helps: This helps new mothers and healthcare providers understand the complexities of childbirth experiences and mothering behaviors.
Genomic evolution and natural history of myeloproliferative neoplasms on therapy.
2026
Cancer discovery
Leongamornlert D, Lee J, Kamizela AE, To K, Myers D +14 more
Plain English This study looked at how certain blood cancers develop over time in patients receiving treatment. Researchers analyzed genetic changes in 30 patients and found that those whose disease progressed to a more severe form had specific genetic alterations, such as the loss of a gene called TP53, while patients with stable disease showed no new mutations. This research highlights the importance of monitoring genetic changes in these patients because it can help track the disease's progression and improve treatment strategies.
Who this helps: This helps patients with chronic blood cancers and their doctors.
Precision Measurement of Neutrino Oscillation Parameters with 10 Years of Data from the NOvA Experiment.
2026
Physical review letters
Abubakar S, Acero MA, Acharya B, Adamson P, Anfimov N +207 more
Plain English This study focused on understanding how neutrinos—tiny, nearly massless particles—change from one type to another as they travel, by analyzing data from the NOvA experiment over ten years. The researchers found a very precise measurement of the difference in mass between two types of neutrinos, which is crucial for understanding their behavior; they reported this difference as about 2.43 x 10^-3 eV². These findings also suggest that the normal mass ordering of neutrinos is significantly more likely than an inverted ordering, which has important implications for physics theories about the universe.
Who this helps: This helps scientists and researchers studying particle physics and the fundamental forces of nature.
Open vs tubular rate of re-operation for incidental durotomies after lumbar microdiscectomies: a propensity matched analysis.
2025
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
McClain E, Gupta B, Zane L, DeFelice J, Woodhouse C +6 more
Plain English This study looked at a surgery complication called incidental durotomy (ID), which can happen during spine surgeries and lead to longer hospital stays and other issues. Researchers compared 192 patients who had minimally invasive surgeries to 2,902 patients who had traditional open surgeries. They found that ID occurred in 3.1% of patients overall, with similar rates in both groups—3.2% in the open surgery group and 3.1% in the minimally invasive group—and only one patient in the open group needed additional surgery for another issue, showing no significant difference between the two methods.
Who this helps: This research helps patients undergoing lumbar microdiscectomies by providing insights on the risks associated with different surgical approaches.
Characterizing stutter in single cells and the impact on multi-cell analysis.
2025
Forensic science international. Genetics
Vandepoele ACW, Novotna N, Myers D, Marciano MA
Plain English This study examined the behavior of "stutter," which are errors that occur during DNA analysis, particularly when analyzing very small samples, like those from a single cell. The researchers found that stutter levels were much higher in single-cell samples compared to larger samples, making it harder to accurately interpret DNA mixtures. For example, the percentage of stutter increased significantly as fewer cells were analyzed, which means interpreting these low-level samples requires careful attention.
Who this helps: This benefits forensic scientists and labs analyzing small DNA samples from crime scenes or biological evidence.
Knowledge of Pelvic Floor Disorders in English- and Spanish-Speaking Postpartum Patients.
2025
Urogynecology (Philadelphia, Pa.)
Siddique M, Passarelli E, Shi C, Myers D
Plain English This study looked at how much postpartum patients know about urinary incontinence and pelvic organ prolapse, comparing English- and Spanish-speaking patients. It found that only 10% of Spanish-speaking patients correctly answered enough questions about urinary incontinence, compared to 40% of English-speaking patients. Both groups had limited knowledge, and this is important because it shows a clear need for better education on these conditions for new mothers.
Who this helps: This helps postpartum patients by highlighting the need for improved educational resources in both English and Spanish.
Plain English This study looked at how researchers measure and use spatial social polarization (SSP) in public health, which is about how different social and economic groups are spread out in certain areas. The review found 117 studies primarily from the U.S., and most of them (about 64) used only one way to measure SSP, while some used up to five different measures to get a clearer picture. Understanding these different ways of measuring SSP is important because it can help researchers study how social factors affect health outcomes more accurately.
Who this helps: This helps public health researchers and policymakers.
A participatory photovoice investigation of community assets, barriers, and opportunities to curb the opioid epidemic.
2025
Journal of substance use and addiction treatment
Balvanz P, Olvera RG, Booty M, McSwiggan J, Damato-MacPherson C +23 more
Plain English This research studied how communities can better address the opioid crisis by using a method called Photovoice, where participants share their experiences through pictures and discussions. In total, 127 people took part in 21 projects across Kentucky, Massachusetts, and Ohio, sharing important themes like the need for peer support, collaboration among services, and resources to improve living conditions. These insights are crucial for developing effective strategies to combat the opioid epidemic at the community level.
Who this helps: This benefits patients, community organizations, and policymakers working to reduce the impact of opioid use.
A social engagement technology-based randomized controlled trial for older adults: Outcomes and lessons learned.
2025
Contemporary clinical trials communications
Mois G, Lydon EA, Danilovich MK, Myers D, Chen XS +2 more
Plain English This study explored how videoconferencing can help older adults feeling lonely or socially isolated by connecting them with others through online social events. Out of 99 participants, those who joined the eight-week program experienced less loneliness and more social activities, with many reporting increased computer skills and enjoyment from interacting with others. This matters because it shows that technology can effectively improve social connections for older adults, especially those with different levels of cognitive abilities.
Who this helps: This helps older adults struggling with loneliness and their caregivers.
To err is human: lessons from prolapse studies to identify and strategies to reduce data errors.
2025
American journal of obstetrics and gynecology
Myers D, Werth A, Whitworth R, Menefee S, Visco A +6 more
Plain English This study looked at how to improve the accuracy of data collected in research on pelvic organ prolapse, a condition that affects the pelvic floor. The researchers found many errors, particularly mistakes in data entry and measuring techniques, with issues like incorrect sign errors and inaccurate assessments being the most common. They created better reporting forms and trained staff to reduce these errors, which is important for ensuring reliable results in medical research that guides treatment decisions.
Who this helps: This helps doctors and researchers working on pelvic floor disorders.
Vaccination protects against COVID-associated pulmonary fibrin deposition.
2025
Journal of virology
Ireland J, Myers D, Huang C, Allen C, Roth G +10 more
Plain English This study looked at how COVID-19 vaccines affect lung problems caused by the virus in 43 patients. It found that vaccinated individuals were less likely to experience severe lung disease because the vaccines helped prevent a harmful clotting process called pulmonary fibrin formation in their lungs. Specifically, no viral-induced fibrin was found in the lungs of vaccinated patients, while it was present in those who were not vaccinated, highlighting that lung fibrin levels can be a better sign of severe COVID than standard blood tests.
Who this helps: This benefits patients and healthcare providers by providing insights into how vaccination can protect against severe lung issues from COVID-19.
Navigating the future of artificial intelligence technologies for improving the care of older adults.
2025
Innovation in aging
Abadir M, Dineen W, Myers D, Yu S, Phan P
Plain English This research examines how artificial intelligence (AI) can improve care for older adults, focusing on important areas such as health, medication management, mental support, and mobility. The study found that while AI can offer valuable support, like personalized medicine and fall detection, there are major gaps in its use, such as not including diverse older adults in research and the risk of disparities in access to these technologies. This is important because as our population ages, we need innovative solutions to meet the health care needs of older adults effectively and equitably.
Who this helps: Older adults and their caregivers.
Dual-Baseline Search for Active-to-Sterile Neutrino Oscillations in NOvA.
2025
Physical review letters
Acero MA, Acharya B, Adamson P, Anfimov N, Antoshkin A +204 more
Plain English This study looked for signs that certain types of tiny particles called neutrinos can change into a type that is harder to detect, known as sterile neutrinos. Researchers used data from NOvA detectors and found no evidence of this transformation, giving a 90% confidence that active neutrinos do not turn into sterile ones under the conditions studied. Their findings also set stricter limits on the possible existence of sterile neutrinos, which is important because it clarifies existing theories in particle physics.
Who this helps: This helps scientists working on neutrino research and understanding fundamental physics.
Work-related injury or work-related pain? A qualitative investigation of work-related pain and injury management among rehabilitation professionals1.
2024
Work (Reading, Mass.)
Evans KW, Myers D, Rockefeller K
Plain English This study looked at the experiences of rehabilitation professionals, like physical and occupational therapists, who work in hospitals. Although they reported no work-related injuries over eight years, many admitted they often worked in pain due to the demands of their job. This finding indicates that the true extent of pain and discomfort among these workers is likely hidden, as they tend to self-manage their pain rather than report it.
Who this helps: This helps rehabilitation professionals by highlighting the need for better recognition and support for work-related pain in their field.
Dietary Intake and Symptom Severity in Women with Fecal Incontinence.
2024
International urogynecology journal
Andy UU, Iriondo-Perez J, Carper B, Richter HE, Dyer KY +7 more
Plain English This study looked at how the amount of fat and fiber in the diets of women with fecal incontinence (FI) affects the severity of their symptoms. It involved 186 women and found that while they consumed more fat than recommended and less fiber, there was no strong link between dietary fat or fiber intake and the severity of FI symptoms. However, there was a small suggestion that higher fat intake might coincide with fewer days without incidents of FI.
Who this helps: This research helps women suffering from fecal incontinence and their healthcare providers understand the limited role diet may play in symptom severity.
Apical Suspension Repair for Vaginal Vault Prolapse: A Randomized Clinical Trial.
2024
JAMA surgery
Menefee SA, Richter HE, Myers D, Moalli P, Weidner AC +8 more
Plain English Researchers tested three surgical methods to fix vaginal vault prolapse in women who had previously undergone hysterectomy. They found that after three years, sacrocolpopexy had a failure rate of 28%, transvaginal mesh had 29%, and native tissue repair had a higher failure rate of 43%, making sacrocolpopexy the most effective option. This study is important because it helps women and doctors choose the best surgical approach for treating this uncomfortable condition with low risks of complications.
Who this helps: Women suffering from vaginal vault prolapse.
Methods and baseline characteristics for a social engagement technology-based randomized controlled trial for older adults.
2024
Contemporary clinical trials communications
Lydon EA, Mois G, Shende SA, Myers D, Danilovich MK +2 more
Plain English This study examined how a video conferencing platform called OneClick can help older adults engage socially, especially those who may struggle to get out due to transportation issues. Researchers assigned 99 older adults, aged 60 to 99, to either participate in social events twice a week for 8 weeks or be in a waitlist group. Their findings will show how well this technology works in boosting social connections and acceptance among older adults with different levels of cognitive ability, which is crucial for their overall well-being.
Who this helps: This benefits older adults who may be isolated, especially those living alone or with cognitive challenges.
Prophylactic closed-incisional negative pressure wound therapy following posterior instrumented spinal fusion: a single surgeon's experience and cost-benefit analysis.
2024
Neurosurgical review
Kramer DE, Bharthi R, Myers D, Chang P, Dabecco R +2 more
Plain English This study looked at how well a specific treatment called closed-incisional negative pressure wound therapy (ciNPWT) works to prevent infections and other complications after spine surgery. Researchers found that patients using ciNPWT had fewer issues: 8.3% experienced surgical site infections (SSIs) compared to 21.2% of those using standard dressings, and wound dehiscence (where the wound reopens) occurred in 21.5% versus 34.1%. Using ciNPWT not only helped reduce these complications but also saved money, with potential savings of about $21,662 for each avoided SSI.
Who this helps: This helps patients undergoing spine surgery and their doctors by reducing complications and healthcare costs.
In-vessel design of a two-color heterodyne laser interferometer system for SPARC.
2024
The Review of scientific instruments
Hawke JN, LaCapra M, Ilagan J, Jean M, Ouellet S +10 more
Plain English This research explores a new system for observing plasma (a hot, ionized gas) inside a machine called SPARC. The team designed a special setup using two infrared lasers, which significantly improves the system's ability to monitor plasma density and protect sensitive components. They ensured these optical parts could handle extreme conditions while maintaining stability, which is crucial for the system's operation.
Who this helps: This helps researchers and engineers working on plasma technology and fusion energy.
Clinical assessment of patient outcomes post percutaneous pulmonary valve implantation: Insights from a single tertiary centre.
2024
Global cardiology science & practice
Saluja S, Myers D, Keavney BD, Keshavarzi F, Anderson SG
Plain English This study looked at how well a device called the percutaneous pulmonary valve (PPV) works for patients with certain heart problems affecting blood flow. Researchers assessed 41 patients who received the PPV and found that it significantly lowered pressure in the heart, with a drop from about 61.6 mmHg to 41.9 mmHg. This means that patients can experience better heart function and possibly an improved quality of life after the procedure.
Who this helps: This helps patients with congenital heart defects affecting blood flow.
Search for CP-Violating Neutrino Nonstandard Interactions with the NOvA Experiment.
2024
Physical review letters
Acero MA, Acharya B, Adamson P, Aliaga L, Anfimov N +201 more
Plain English This study looked at how neutrinos, which are tiny particles, interact with matter and whether these interactions break a fundamental symmetry called charge-parity (CP) symmetry. Researchers used data from the NOvA Experiment and found that certain parameters related to these interactions were constrained: they determined that the effects of two specific types of interactions are no larger than 0.3 and 0.4, which helps clarify our understanding of neutrino behavior. This matters because it helps scientists better understand the universe's fundamental laws and how neutrinos might affect our knowledge of particle physics.
Who this helps: This helps physicists and researchers studying fundamental particles and the forces that govern the universe.
Accuracy of CT-Derived Patient-Specific Instrumentation for Total Ankle Arthroplasty: The Impact of the Severity of Preoperative Varus Ankle Deformity.
Plain English This study looked at how well a specific method using CT scans can accurately place implants during total ankle replacement surgery, especially for patients with varying degrees of ankle deformity. Out of 32 patients, an impressive 96.9% achieved the desired implant alignment after surgery, even though they had different levels of preoperative deformities. This is important because it shows that even those with significant deformities can still have successful surgery outcomes using this advanced technique.
Who this helps: This research benefits patients with severe ankle deformities considering total ankle replacement surgery.
Association Between Enlarged Genital Hiatus and Composite Surgical Failure After Vaginal Hysterectomy With Uterosacral Ligament Suspension.
2023
Urogynecology (Philadelphia, Pa.)
Bradley MS, Sridhar A, Ferrante K, Andy UU, Visco AG +6 more
Plain English This study looked at how the size of the genital opening, called the genital hiatus, after a specific type of surgery (vaginal hysterectomy with uterosacral ligament suspension) affects the chances of pelvic organ prolapse coming back. Researchers found that 50% of women with a persistently enlarged genital hiatus experienced a recurrence of prolapse, compared to only 12% of those whose genital hiatus was stable and normal. This is important because it highlights that women with an enlarged genital hiatus after surgery may be at a much higher risk for complications, indicating that doctors should monitor this condition closely.
Who this helps: This helps women undergoing vaginal hysterectomy, their doctors, and healthcare providers.
Characteristics associated with subjective and objective measures of treatment success in women undergoing percutaneous tibial nerve stimulation vs sham for accidental bowel leakage.
2023
International urogynecology journal
Luchristt D, Carper B, Balgobin S, Meyer I, Myers D +6 more
Plain English In this study, researchers looked at the effectiveness of a treatment called percutaneous tibial nerve stimulation (PTNS) compared to a fake treatment (sham) in women with accidental bowel leakage (ABL). They found that PTNS had success rates of 65%, 57%, and 46% based on different criteria for improvement, but no specific group of women responded better to PTNS than to the sham treatment. This matters because it highlights the need for better ways to measure what makes a treatment truly effective for patients with ABL.
Who this helps: This helps women with accidental bowel leakage and their doctors.
HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL.
2023
Blood advances
McNerney KO, Si Lim SJ, Ishikawa K, Dreyzin A, Vatsayan A +28 more
Plain English This study looked at the effects of a treatment called tisagenlecleucel in children and young adults with B-cell acute lymphoblastic leukemia (B-ALL) and found that a condition known as HLH-like toxicities (HLH-LTs) can significantly impact survival rates. Out of 185 patients, 26 (about 14%) developed HLH-LTs, which led to a much lower one-year survival rate of 25.7% compared to 80.1% for those without these toxicities. This information is important because it highlights the need for better management strategies for patients who experience HLH-LTs after treatment, as they face a much higher risk of relapse and death.
Who this helps: This helps doctors and healthcare providers in treating children and young adults with B-ALL.
Prevalence of workplace violence against young workers in the United States.
2023
American journal of industrial medicine
Rauscher K, Casteel C, Davis J, Myers D, Peek-Asa C
Plain English This study examined the frequency of workplace violence experienced by young workers in the United States, specifically those aged 14 to 24. It found that 60% of these young workers reported experiencing some form of violence, with 53% facing verbal abuse that made them feel scared, and 24% experiencing sexual harassment. This highlights a significant issue, particularly in industries like healthcare and hospitality, where young workers are especially vulnerable to violence.
Who this helps: This benefits young workers and their employers by raising awareness of workplace safety issues.
Differences Between Patients With Diabetes Mellitus and Those Without in Cases of Necrotizing Fasciitis.
2023
Cureus
DeGenova DT, Hyland SS, Peabody T, Schmitz NP, Myers D +2 more
Plain English This study looked at patients with necrotizing fasciitis (a severe skin infection) to see how those with diabetes differ from those without the condition. Out of 115 patients reviewed, those with diabetes had a higher average risk score (9.02) compared to non-diabetics (7.24), and they were significantly more likely to need amputations. The overall death rate for these infections was 26.1%, with 30.9% for diabetic patients compared to 18.9% for non-diabetic patients.
Who this helps: This research benefits doctors and healthcare providers by highlighting the increased risks for diabetic patients with necrotizing fasciitis.
Intraoperative Predictors of Sacral Neuromodulation Implantation and Treatment Response: Results From the ROSETTA Trial.
2023
The Journal of urology
Gill BC, Thomas S, Barden L, Jelovsek JE, Meyer I +7 more
Plain English This study examined how intraoperative data can predict the success of a treatment called sacral neuromodulation for women with urgent urinary incontinence. Out of 161 women, 139 (86%) experienced initial success with the treatment, but specific measurements taken during surgery did not reliably forecast long-term results. Notably, the position of the electrode seemed to play a significant role, especially in predicting outcomes—the best responses were linked to improved results, while some positions were associated with poorer performance.
Who this helps: This research helps doctors who treat women with urgent urinary incontinence by providing insights on the effectiveness of different surgical techniques.
Maternal cardiac disease and perinatal outcomes in a single tertiary care center.
2023
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Gonzalez JM, Harris I, Jimenez Ramirez N, Myers D, Killion M +2 more
Plain English This study looked at the effects of maternal heart disease on pregnancy outcomes by comparing women with heart issues to those without during deliveries from 2008 to 2013. They found that women with maternal cardiac disease had higher chances of complications such as preterm birth (especially before 34 weeks), growth issues for the baby, and longer hospital stays. For instance, there were increased odds of preterm birth in 51% of cases involving cardiac disease compared to healthier pregnancies. This matters because it highlights the need for specialized care for pregnant women with heart conditions to improve both mother and baby health outcomes.
Who this helps: This helps patients with maternal heart disease and their healthcare providers.
Humoral and cellular response to the COVID-19 vaccine in immunocompromised children.
2023
Pediatric research
Morgans HA, Bradley T, Flebbe-Rehwaldt L, Selvarangan R, Bagherian A +16 more
Plain English A prospective study of 37 immunocompromised children found that most had detectable antibody responses after two COVID-19 vaccine doses, and a third dose significantly boosted both antibody levels and T-cell responses, bringing T-cell response rates to 100%. The study is the first to measure both immune response types after the third dose in immunocompromised children. The results support the recommendation for a third vaccine dose in this vulnerable population.
Patient-reported outcomes from the JADE COMPARE randomized phase 3 study of abrocitinib in adults with moderate-to-severe atopic dermatitis.
2022
Journal of the European Academy of Dermatology and Venereology : JEADV
Thyssen JP, Yosipovitch G, Paul C, Kwatra SG, Chu CY +6 more
Plain English This study looked at how well a medication called abrocitinib helps adults with moderate-to-severe atopic dermatitis, a skin condition that causes itching and redness. After 16 weeks of treatment, 21.3% of patients taking the higher dose of abrocitinib reported significant improvements in their symptoms, compared to only 4.8% of those on a placebo. Abrocitinib also helped a majority of patients achieve better quality of life scores and reduced their nighttime itching.
Who this helps: This benefits patients suffering from atopic dermatitis, particularly those with moderate-to-severe symptoms.
Directed Hypercapnia as a Strategy to Wean Extracorporeal Membrane Oxygenation in COVID-19 Pneumonia.
2022
The Annals of thoracic surgery
Kluis A, Shih E, Squiers JJ, DiMaio JM, Sheasby J +2 more
Plain English This study looked at how directing higher levels of carbon dioxide in the blood, known as hypercapnia, can help patients with COVID-19 pneumonia reduce their reliance on a treatment called extracorporeal membrane oxygenation (ECMO). In this report involving 5 patients, using this method successfully helped them transition away from prolonged ECMO support. This is important because it offers a potential strategy for managing severe respiratory failure in COVID-19 patients effectively.
Who this helps: This helps patients with severe COVID-19 pneumonia needing advanced respiratory support.
P- and E- selectin in venous thrombosis and non-venous pathologies.
2022
Journal of thrombosis and haemostasis : JTH
Purdy M, Obi A, Myers D, Wakefield T
Plain English This research looked at P- and E-selectin proteins and their roles in blood clots, specifically in venous thrombosis. The findings showed that blocking these proteins can reduce the formation of clots and damage to vein walls without increasing bleeding risks, suggesting a safer treatment option. This is important because current blood-thinning treatments can cause severe bleeding and don’t always prevent long-term complications.
Who this helps: This helps patients suffering from blood clots and doctors seeking better treatment options.
Long-term Urinary Outcomes After Transvaginal Uterovaginal Prolapse Repair With and Without Concomitant Midurethral Slings.
2022
Female pelvic medicine & reconstructive surgery
Giugale L, Sridhar A, Ferrante KL, Komesu YM, Meyer I +8 more
Plain English This study looked at how urinary function changes over time for women undergoing surgery to fix pelvic organ prolapse, specifically comparing those who had a midurethral sling placed at the same time versus those who didn't. Researchers found that, after five years, women who had a sling during a hysterectomy reported better urinary function and less leakage of urine, but this benefit wasn't seen for those who had a different type of surgery. Understanding these outcomes helps doctors make better decisions about whether to place a sling during prolapse repair, aiming to improve women's long-term urinary health.
Who this helps: This helps patients undergoing pelvic organ prolapse repair surgery.
Left Ventricular Thrombus of Unknown Etiology in a Patient With COVID-19 Disease With No Significant Medical History.
2022
Cardiovascular revascularization medicine : including molecular interventions
Russell J, Wagoner M, DuPont J, Myers D, Muthu K +1 more
Plain English This study examined a 44-year-old man with COVID-19 who developed a blood clot in his heart (left ventricular thrombus) even though he didn't have any significant health issues beforehand. Despite receiving treatment to prevent blood clots while in the hospital, he experienced serious complications when the clot broke loose and blocked important coronary arteries, requiring a medical procedure to remove it. This is important because it highlights how COVID-19 can lead to unexpected blood clotting problems, even in younger patients without prior health issues.
Who this helps: This helps doctors and healthcare providers understand the risks of blood clots in COVID-19 patients.
RSV-associated hospitalization in adults in the USA: A retrospective chart review investigating burden, management strategies, and outcomes.
2022
Health science reports
Walsh E, Lee N, Sander I, Stolper R, Zakar J +3 more
Plain English Researchers examined the impact of respiratory syncytial virus (RSV) on adults in the U.S. by looking at hospital records from two RSV seasons. They found that 73% of the 379 adults studied came to the emergency room, with an average age of 60 years and a hospital stay lasting about 6 days. Most patients received respiratory support during treatment, and many needed follow-up care after leaving the hospital, highlighting the significant strain RSV places on healthcare systems.
Who this helps: Patients and healthcare providers dealing with RSV in adults.
Proprotein Convertase Subtilisin Kexin 9 (PCSK9) and nonHDL particles rise during normal pregnancy and differ by BMI.
2022
Journal of clinical lipidology
Wild RA, Weedin E, Cox K, Zhao YD, Wrenn DS +5 more
Plain English This study examined how pregnancy and body weight affect levels of certain lipids and a protein called PCSK9 in women. Researchers found that total PCSK9, LDL cholesterol, and non-HDL particles all increased during pregnancy, peaking in the second half, especially in women who are overweight or obese. Recognizing these changes is important for understanding lipid management during pregnancy, as it may influence health outcomes for both mothers and their babies.
Who this helps: This helps pregnant women, especially those who are overweight or obese, and their healthcare providers.
Optimisation of the additive manufacturing parameters of polylactic acid (PLA) cellular structures for biomedical applications.
2022
Journal of the mechanical behavior of biomedical materials
Myers D, Abdel-Wahab A, Hafeez F, Kovacev N, Essa K
Plain English This study looked at how to improve the 3D printing process for creating special structures called lattices using a material called polylactic acid (PLA). Researchers found that using a layer height of 0.16 mm, a print speed of 50 mm/s, and a flow rate of 90% led to stronger and more accurate lattice structures. Specifically, the Schoen Gyroid lattice was about 18% stronger than another type, the Schwarz Primitive, making it better suited for medical uses like orthopedic implants, where strength and precision are crucial.
Who this helps: This research benefits patients needing orthopedic implants and doctors who create these solutions.
Plain English This study looked at how long surgeries take for obese patients with fractures in the pelvis and hip compared to non-obese patients. Researchers found that obese patients required significantly longer surgery times, with acetabular fracture surgeries taking about 20% longer and pelvic ring surgeries taking about 15% longer. This matters because longer surgeries can lead to higher risks of complications and may warrant special billing adjustments for healthcare providers due to the increased difficulty involved.
Who this helps: This helps doctors and healthcare facilities when planning surgeries for obese patients.
Decreased health care expenditure and average length of therapy with facilitated transition discharge program for patients receiving negative pressure wound therapy.
2022
Wounds : a compendium of clinical research and practice
Boti L, Soloway L, Myers D, Pillai D, Zabihi J
Plain English This study looked at how a special discharge program for patients receiving negative pressure wound therapy (a treatment for wounds) affects hospital stays and costs. It found that patients in the program left the hospital 1.8 days earlier and their care was potentially $5,071 cheaper per patient. The findings matter because shorter hospital stays can lead to lower costs and better resource use in healthcare.
Who this helps: This helps patients and hospitals by reducing costs and improving efficiency in wound treatment.