Dr. Funderburk investigates various medical conditions and treatments mainly related to pediatric surgery, brain disorders, and hormone regulation. He has conducted groundbreaking research on tuberous breast deformity in boys, which is a rare condition that can impact a child's self-esteem and body image. His studies also explore the molecular changes in Alzheimer's disease, identifying significant proteins that may lead to better understanding and treatment options for this condition. Additionally, he analyzes how genetics and environmental factors contribute to diseases like Parkinson's, helping to refine future treatments for patients suffering from such conditions.
Key findings
In a 2019 study, Dr. Funderburk successfully treated tuberous breast deformity in a 12-year-old boy, resulting in good patient satisfaction six months post-surgery.
His 2009 research on Alzheimer's disease identified 81 specific proteins that were significantly different in patients compared to healthy individuals, providing new potential targets for treatment.
In a study using fruit flies, exposure to the herbicide paraquat accelerated Parkinson's symptoms more quickly in males than females, revealing important factors influencing the disease's progression.
Frequently asked questions
Does Dr. Funderburk study conditions like tuberous breast deformity?
Yes, he specializes in surgical interventions for rare conditions such as tuberous breast deformity, particularly in prepubescent boys.
What does Dr. Funderburk's research on Alzheimer's involve?
His research identifies unique proteins in Alzheimer's patients that could lead to new treatment strategies for the disease.
Is Dr. Funderburk's work relevant for Parkinson's disease patients?
Yes, his studies on the interaction between genetics and environmental factors provide insights that can inform potential treatments for Parkinson's disease.
Publications in plain English
Correction of the tuberous breast deformity in a prepubescent male patient: A surgical approach to an unusual problem.
Plain English The study focused on a rare condition called tuberous breast deformity in a 12-year-old boy who had unusual breast shape and enlargement. The surgical treatment involved removing excess breast tissue and skin and transplanting the nipple, which resulted in a satisfactory appearance and good patient satisfaction after six months. This matters because it provides a new approach to treating a condition that has not been well-studied in boys, helping to improve their body image and quality of life.
Who this helps: This helps prepubescent boys dealing with tuberous breast deformities.
Population Dynamics of Frankliniella bispinosa (Thysanoptera: Thripidae) and the Predator Orius insidiosus (Hemiptera: Anthocoridae) as Influenced by Flower Color of Lagerstroemia (Lythraceae).
2015
Environmental entomology
Funderburk C, Funderburk J, Tyler-Julian K, Srivastava M, Knox G +2 more
Plain English This study examined how the color of crapemyrtle flowers affects the populations of a plant-eating insect called Frankliniella bispinosa and its predator, Orius insidiosus. Researchers found that both the herbivores and their predators preferred white flowers over other colors. The white 'Acoma' flowers not only attracted more predators but also prevented the plant-eating insects from increasing in number, showing that these flowers are very effective in managing pest populations.
Who this helps: This benefits gardeners and landscapers looking to control pests naturally.
Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease.
2009
Journal of proteome research
Gozal YM, Duong DM, Gearing M, Cheng D, Hanfelt JJ +4 more
Plain English This study examined brain samples from people with Alzheimer's disease (AD) to identify specific proteins that are significantly altered compared to healthy individuals and those with other brain disorders. They found 81 proteins that were notably different in AD patients, including known ones like beta-amyloid and tau, and newly recognized ones like serine protease 15 and 14-3-3 eta. This research is important because it helps us understand the unique features of Alzheimer's and could lead to new treatments for the disease.
Who this helps: Patients with Alzheimer's disease and their caregivers.
Interaction of genetic and environmental factors in a Drosophila parkinsonism model.
2007
The Journal of neuroscience : the official journal of the Society for Neuroscience
Chaudhuri A, Bowling K, Funderburk C, Lawal H, Inamdar A +2 more
Plain English This study looked at how genetics and environmental factors interact to influence Parkinson's disease using fruit flies as a model. Researchers found that exposure to the herbicide paraquat caused symptoms similar to Parkinson's in male fruit flies more quickly than in females. They discovered that mutations affecting dopamine levels played a crucial role; in particular, boosting dopamine production helped protect against damage from paraquat, while reducing dopamine made fruit flies more susceptible.
Who this helps: This research benefits scientists studying Parkinson's disease and may inform treatments for patients.
Political legitimacy and approval of political protest and violence among children and adolescents.
1975
Journal of youth and adolescence
Funderburk C
Plain English This study looked at how children and teenagers in a Florida town view political legitimacy and how that influences their opinions on political protest and violence. The researchers found that beliefs in political legitimacy significantly affect how young people feel about political violence, but these beliefs do not play a major role in their views on protest actions. Understanding these connections is important because it helps shed light on what influences young people's views on serious political issues.
Who this helps: This helps educators and policymakers understand youth attitudes towards political actions.
Studies on growth hormone secretion. VII. Effects of somatostatin on plasma GH, insulin, and glucagon in sheep.
1975
Diabetes
Bryce D, Yeh M, Funderburk C, Todd H, Hertelendy F
Plain English This study looked at how a synthetic version of somatostatin, a hormone that can stop the release of other hormones, affects the levels of growth hormone (GH), insulin, and glucagon in sheep. The researchers found that when they infused somatostatin, it reduced GH levels significantly—by about 50% and up to 80%—after a specific treatment that normally raises GH levels. This is important because it could help us understand how hormone release works in the body, which might inform treatments for hormone-related issues.
Who this helps: This benefits doctors and researchers studying hormone treatments.
Joseph Gorvetzian Libby R Copeland-Halperin John Nigriny Abdullah Bakhsh Bryan Morse Patrick Meloy Katie Dean Jeffrey Siegelman Todd Taylor Joe Funderburk
Physician data sourced from the
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Publication data from
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Plain-English summaries generated by AI.
Not medical advice.