Dr. Raybuck studies conditions affecting heart health, including heart attacks, heart valve issues, and complications from cardiovascular procedures. His research emphasizes the importance of timely treatment for heart attacks and explores new imaging techniques to guide treatments for complex conditions, such as unicuspid aortic valve and left atrial appendage issues. He also investigates how gender impacts outcomes for heart procedures, and how machine learning can enhance patient risk assessments. Overall, his work strives to improve care for patients undergoing various cardiac interventions.
Key findings
In African hospitals, the average door-to-needle time for treating severe heart attacks was found to be 74.8 minutes, with only 36.3% of patients receiving timely care within the recommended 30 minutes.
Women undergoing left atrial appendage occlusion experienced adverse events at a rate of 27.2% compared to 19.8% for men, indicating a need for closer monitoring of female patients post-procedure.
95% of patients with the WATCHMAN FLX™ device showed signs of hypoattenuated thickening (HAT) on cardiac computed tomography angiography, suggesting a high risk for blood clots.
The use of 3D transesophageal echocardiography (TEE) helped reduce contrast dye exposure for patients with kidney dysfunction undergoing transcatheter aortic valve replacement, showing similar kidney health outcomes post-procedure.
3.8% of over 10,000 patients developed device-related thrombus after left atrial appendage occlusion, leading to ischemic events 4 to 5 times more often compared to those without thrombus.
Frequently asked questions
Does Dr. Raybuck study heart attacks?
Yes, he studies the management of heart attacks, particularly the timing of treatment in hospitals.
What treatments has Dr. Raybuck researched?
He has researched several heart procedures including left atrial appendage occlusion, transcatheter aortic valve replacement, and advanced imaging techniques to guide these treatments.
Is Dr. Raybuck's work relevant to women undergoing heart procedures?
Yes, his research highlights significant gender differences in outcomes for women undergoing heart procedures, indicating they may need more careful monitoring.
What imaging techniques does Dr. Raybuck use in his research?
He utilizes various imaging techniques such as cardiac computed tomography angiography and 3D transesophageal echocardiography to guide heart procedures.
Do Dr. Raybuck's studies address complications after heart procedures?
Yes, he studies the incidence of complications like device-related thrombus and assesses outcomes to improve patient management after heart interventions.
Publications in plain English
Door-to-needle performance in African ST-elevation myocardial infarction management: A systematic review and meta-analysis.
2025
JRSM cardiovascular disease
Sama C, Okorigba E, Rana S, Abdelazeem B, Qureshi H +10 more
Plain English Researchers studied how quickly hospitals in Africa treat patients with severe heart attacks, specifically looking at the time between a patient arriving at the hospital and receiving lifesaving treatment. They found that the average time was about 74.8 minutes, which is significantly longer than the recommended maximum of 30 minutes. Only 36.3% of patients received treatment within the suggested timeframe, showing a critical need for improvements in emergency care for heart attack patients.
Who this helps: This benefits patients experiencing heart attacks and healthcare providers in African hospitals.
Case report: unravelling the puzzle of unicuspid aortic valve with multimodality imaging.
2024
European heart journal. Case reports
Pang L, Colantonio MA, Arvon J, Raybuck B, Balla S
Plain English This study looked at a rare heart condition called unicuspid aortic valve (UAV) in a 61-year-old woman who was experiencing shortness of breath. Doctors found that she had severe aortic stenosis (narrowing of the valve), but different imaging tests showed varying levels of severity. By using advanced imaging techniques, they identified her specific type of UAV, which helped guide her treatment plan.
Who this helps: This research benefits doctors in diagnosing and treating patients with complex heart valve issues.
Evaluating Gender-based Differences in Clinical Outcomes for Patients Undergoing Left Atrial Appendage Occlusion: A Single Centre Experience.
2023
Current problems in cardiology
Hana D, Miller T, Chaker Z, Chobufo MD, Khan A +9 more
Plain English This study looked at the differences between men and women who underwent a specific heart procedure called left atrial appendage occlusion at West Virginia University. Researchers found that women experienced more serious problems during their hospital stay, with 27.2% facing adverse events compared to 19.8% of men, including more bleeding incidents (10.2% vs. 6.4%). These findings highlight that women may need closer monitoring and care after this procedure due to their higher risk of complications, even though their long-term outcomes were similar to men.
Who this helps: This helps doctors and healthcare providers better care for women undergoing this heart procedure.
3D Transesophageal Echocardiography for Guiding Transcatheter Aortic Valve Replacement Without Prior Cardiac Computed Tomography in Patients With Renal Dysfunction.
2022
Cardiovascular revascularization medicine : including molecular interventions
Hana D, Miller T, Skaff P, Seetharam K, Suleiman S +10 more
Plain English This study looked at whether using a 3D ultrasound of the heart (called 3D transesophageal echocardiography, or TEE) instead of a cardiac CT scan could help patients with kidney issues avoid damage to their kidneys during a heart valve replacement procedure (TAVR). Researchers compared 396 patients who had the CT scan to 54 patients who only had the 3D ultrasound. They found that those who used TEE had less exposure to contrast dye, which is often harmful to the kidneys; even though the TEE group had worse kidney function to start with, both groups showed similar kidney health after the procedure.
Who this helps: This approach benefits patients with chronic kidney disease undergoing heart valve replacement.
Cardiac Computed Tomography Angiography for Device-Related Thrombus Assessment After WATCHMAN FLX™ Occluder Device Implantation: A Single-Center Retrospective Observational Study.
2022
Cardiovascular revascularization medicine : including molecular interventions
Miller T, Hana D, Patibandla S, Guzman DB, Avalon JC +11 more
Plain English This study examined how well a type of imaging called cardiac computed tomography angiography (CCTA) can detect blood clots related to a heart device called the WATCHMAN FLX™. Among 43 patients who had the device implanted, 95% showed a common sign called hypoattenuated thickening (HAT) on CCTA. The findings suggest that certain device features and how they relate to HAT might indicate a higher risk for blood clots, highlighting the potential importance of CCTA in monitoring patients after this heart procedure.
Who this helps: This benefits patients with the WATCHMAN FLX™ device and their doctors by providing a safer way to monitor for blood clots.
Snare and track (SNACK) technique: a novel approach for successful placement of an intracardiac echocardiogram catheter in the left atrium: a case report.
2022
European heart journal. Case reports
Kawsara A, Raybuck B
Plain English This study explored a new method for easily placing a special ultrasound catheter in the left atrium of the heart, which is important for guiding a procedure to close off a part of the heart called the left atrial appendage. The researchers successfully used this method on a 76-year-old man, enabling them to place the catheter without complications and successfully complete the procedure. This approach can simplify the process for doctors when they face difficult situations during heart procedures.
Who this helps: This helps doctors performing heart procedures, particularly those involving the left atrial appendage.
CT assessment of the left atrial appendage post-transcatheter occlusion - A systematic review and meta analysis.
2021
Journal of cardiovascular computed tomography
Banga S, Osman M, Sengupta PP, Benjamin MM, Shrestha S +8 more
Plain English This research compared two imaging methods—transesophageal echocardiography (TEE) and cardiac computed tomography angiography (CCTA)—to check the left atrial appendage (LAA) after patients had a device placed to close it. The findings showed that CCTA was 2.79 times more likely to find any remaining openings in the LAA compared to TEE. This matters because using CCTA can provide a better assessment of the LAA's condition, potentially leading to improved patient management after the procedure.
Who this helps: Patients who undergo LAA closure procedures.
Outcomes of Routine Intracardiac Echocardiography to Guide Left Atrial Appendage Occlusion.
2020
JACC. Clinical electrophysiology
Alkhouli M, Chaker Z, Alqahtani F, Raslan S, Raybuck B
Plain English This study examined two methods for guiding a procedure that closes off a part of the heart called the left atrial appendage (LAAO) to prevent blood clots, comparing intracardiac echocardiography (ICE) with the traditional transesophageal echocardiography (TEE). Both techniques had very similar success rates, with 97.8% for ICE and 97.4% for TEE, and major complications occurred in 3.3% of ICE patients versus 4.1% for TEE. While ICE had shorter in-room time, it also resulted in higher hospital charges ($76,366 for ICE compared to $71,114 for TEE), but overall costs were about the same for both methods.
Who this helps: This benefits patients undergoing LAAO procedures by providing options for both safety and cost.
Usefulness of Semisupervised Machine-Learning-Based Phenogrouping to Improve Risk Assessment for Patients Undergoing Transcatheter Aortic Valve Implantation.
2020
The American journal of cardiology
Abdul Ghffar Y, Osman M, Shrestha S, Shaukat F, Kagiyama N +4 more
Plain English This study looked at how machine learning can group patients undergoing a specific heart procedure called transcatheter aortic valve implantation (TAVI) based on their health conditions and outcomes. Researchers divided 344 patients into two groups and found five distinct patient groups, with the first group experiencing the fewest complications and the fifth group facing much higher risks of serious problems, such as a 35 times greater chance of dying from heart-related issues during the hospital stay. This matters because it helps doctors better predict which patients are at higher risk after the procedure, which can improve patient care and outcomes.
Who this helps: This helps patients undergoing TAVI and their doctors in making more informed treatment decisions.
1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Mitral Annular Calcification.
2018
Journal of the American College of Cardiology
Guerrero M, Urena M, Himbert D, Wang DD, Eleid M +52 more
Plain English This study looked at the outcomes of a new heart procedure called transcatheter mitral valve replacement (TMVR) in patients with severe mitral annular calcification, a condition that makes surgery risky. Out of 116 patients who had the procedure, 53.7% died within a year, but for those who survived the first 30 days, about 63.6% were still alive after a year and many experienced improved heart function. This research matters because it helps understand the effectiveness and risks of TMVR in high-risk patients, guiding future treatment options.
Who this helps: Patients with severe heart issues and their doctors.
Incidence and Clinical Impact of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion: A Meta-Analysis.
2018
JACC. Clinical electrophysiology
Alkhouli M, Busu T, Shah K, Osman M, Alqahtani F +1 more
Plain English This study looked at the occurrence and effects of device-related thrombus (DRT) after a procedure called left atrial appendage occlusion (LAAO), which helps prevent strokes in certain patients. Out of over 10,000 patients studied, 3.8% developed DRT, and those with DRT had ischemic events (like strokes) 4 to 5 times more often than those without it. Understanding this risk helps improve patient care and management after LAAO procedures.
Who this helps: Patients at risk of stroke and their doctors.
Circulating miRNA in patients with non-alcoholic fatty liver disease and coronary artery disease.
2016
BMJ open gastroenterology
Mehta R, Otgonsuren M, Younoszai Z, Allawi H, Raybuck B +1 more
Plain English This study looked at certain small molecules called microRNAs (miRNAs) in patients who have both non-alcoholic fatty liver disease (NAFLD) and coronary artery disease (CAD). Researchers found that patients with NAFLD and CAD had lower levels of a specific miRNA (miR-132) compared to those who had NAFLD without CAD, while another miRNA (miR-143) was higher in the patients with both conditions. These findings are important because they indicate that changes in miRNA levels could be linked to heart disease in people with liver problems.
Who this helps: This helps doctors and researchers understand better how to treat patients with both liver and heart conditions.
Dual-balloon angioplasty of recoarctation of the aorta.
1987
Texas Heart Institute journal
Moore JW, Pearson CE, Lee DH, Raybuck B
Plain English This study looked at a treatment method called dual-balloon angioplasty for infants who experience recoarctation of the aorta, which is a narrowing of the large artery after it has been corrected surgically. The researchers successfully treated an infant who weighed 9 kilograms by using two small balloons that worked better than the usual methods. This approach is important because it provides a safer and more effective option for infants who may not be able to use larger balloons due to their size.
Who this helps: This helps infants with heart conditions, particularly those who have had previous surgeries.