ANDREA BACH CRAWFORD, MD

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This study looked at the safety and effectiveness of patients undergoing a second lung surgery for cancer between 2012 and 2023. Out of nearly 145,000 surgeries, about 2,700 were second operations. The research found that the major complications or death within 30 days happened in 4.6% of these second surgeries, which is better than the 5.9% rate in patients having their first surgery. This matters because it shows that second surgeries can be done safely and effectively as long as patients are carefully chosen based on their health. Who this helps: This helps patients with lung cancer considering a second surgery, as well as their doctors in planning treatment.

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Researchers discovered a new virus called BluerMoon that attacks bacteria, found in topsoil in Lubbock, Texas. They studied its genetic makeup and classified it as part of a specific group of viruses known as the DJ cluster. This research is important because bacteriophages like BluerMoon could potentially be used to fight bacterial infections. Who this helps: This helps patients and doctors looking for new treatments for bacterial infections.

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This study looked at the differences in access to digital health tools for heart-related care among immigrant communities. It found that these communities face significant challenges, especially in terms of access to technology, which prevents them from getting better healthcare. Using a structured assessment approach, the researchers highlighted the importance of including immigrants in the creation of these digital health tools to ensure that everyone has equal access to vital services. Who this helps: This helps immigrant patients seeking cardiovascular care.

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This study looked at two copper transporters, ATP7A and ATP7B, which are linked to Menkes disease and Wilson disease, to understand their roles in brain function related to noradrenaline signaling. The researchers found that removing ATP7A led to reduced copper levels and neurological damage, while removing ATP7B changed how copper was used in the cells, resulting in an imbalance of important brain chemicals. These findings highlight how each transporter uniquely affects brain health and energy regulation, even when overall copper levels look normal. Who this helps: This helps patients with Menkes and Wilson diseases by clarifying the specific brain issues they face and guiding future treatments.

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This study looked at the short-term success rates of esophagectomy surgeries for esophageal cancer, specifically how many patients had a "textbook outcome," meaning they had no major complications or deaths shortly after surgery. Out of nearly 3,700 patients surveyed between 2016 and 2021, 68% achieved this ideal outcome. Factors like older age, certain health conditions, and complexity of the surgery were linked to not reaching these successful results, pointing to areas where improvements can be made. Who this helps: This research benefits patients undergoing esophagectomy, as well as doctors aiming to improve surgical success rates.

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Researchers gathered in Copenhagen to improve health research and education in Arctic communities. They included 31 participants from various backgrounds, focusing on mentorship for young scholars and ways to collaborate more effectively. Key findings included the need for better coordination in health efforts and the importance of integrating Indigenous knowledge, with plans to develop a mentorship model and enhance ethical research practices over the next few years. Who this helps: This benefits Arctic communities, health researchers, and young scholars.

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The Australian Guidelines for assessing and diagnosing Fetal Alcohol Spectrum Disorder (FASD) were updated in May 2025 after thorough consultation and review of evidence. These new guidelines include 11 key recommendations and aim to improve how practitioners diagnose FASD, with a focus on identifying significant neurodevelopmental impairments and incorporating the needs of First Nations Australians. The guidelines also encourage collaboration between practitioners and families, leading to better support and a more accurate diagnosis. Who this helps: These guidelines benefit patients, families, and healthcare providers involved in diagnosing and supporting individuals with FASD.

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This research paper looks at a condition called feline hippocampal necrosis (FHN) in domestic cats, which involves severe brain damage specifically in the hippocampus, leading to seizures similar to temporal lobe epilepsy. The study clarifies that FHN is not just one disease but can result from various health issues, including tumors or autoimmune responses. Understanding FHN is essential because it helps identify the underlying causes of seizures in cats and informs better treatment options. Who this helps: This helps veterinarians and cat owners in diagnosing and managing cats with seizures.

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This study looked at how frailty, measured by the Modified Frailty Index (mFI-5), affects outcomes for patients undergoing esophagectomy, a surgery for cancer in the esophagus. Researchers analyzed over 5,600 patients and found that those with an mFI-5 score greater than 2 had a higher risk of major complications or death within 30 days of surgery. Understanding this relationship is important because it helps identify patients who may face more significant risks and need closer monitoring after surgery. Who this helps: This helps doctors better assess and manage risks for patients undergoing esophagectomy.

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This study looked at Americans' opinions on authoritarianism and violence related to the government in mid-2025. It found that 15% of respondents believed having a strong leader was more important than democracy, while nearly 10% thought the government should use the military to enforce its policies. These findings highlight a concerning trend of support for authoritarian views and government violence, underlining the need for action to protect democracy in the U.S. Who this helps: This helps policymakers and advocates working to strengthen democratic values and prevent political violence.

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This research looked at how many people in the U.S. believe that political violence is justified and their willingness to engage in it from 2024 to 2025. The study found a slight increase in support for political violence, with 35.6% of participants believing it is usually or always justified to advance political goals, compared to 32.3% the previous year. Specifically, 52.2% of MAGA Republicans felt this way, compared to 32.1% of strong Democrats. This is important because it highlights a growing concern during a critical election year, indicating a need for preventive measures against political violence. Who this helps: This helps policymakers, community leaders, and law enforcement in addressing political violence risks.

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This study looked at veterans who were recently released from prison to understand their challenges and goals as they reintegrate into society. Researchers interviewed 54 veterans and found that they generally aim to secure housing and jobs, access medical care, stay sober, improve their relationships, and avoid going back to prison. Key factors that affected their success included their past military experiences and how they managed stress and relationships after incarceration. Who this helps: This information benefits veterans, their families, and support services working to assist with their transition after prison.

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This study looked at survival rates for lung cancer patients who had either a sublobar resection or a lobectomy after receiving pre-surgery treatment. Out of 2,257 patients, only 148 had sublobar resection; although both surgeries had similar short-term survival, patients with stage III cancer had a lower 5-year survival rate with sublobar resection (48.6%) compared to lobectomy (59.9%). This research highlights that while sublobar resection may be suitable for some patients, lobectomy is generally better for longer-term survival, especially in more advanced cases. Who this helps: This helps lung cancer patients and their doctors make informed decisions about surgery options.

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This study focuses on a trial called the Path to Prevention (P2P) that tests new treatments for early-stage Neuronal Alpha-Synuclein disease, a condition related to Parkinson's disease. The trial will use information and resources from the Parkinson's Progression Markers Initiative (PPMI) to ensure a successful study. This is significant because it is one of the first efforts to create a solid framework for testing interventions for this early stage of the disease, potentially leading to better treatment options. Who this helps: This helps patients with early-stage Neuronal Alpha-Synuclein disease.

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This study focuses on the importance of checking in on children born prematurely or with other health concerns at the age of 4 to see how they are developing before they start school. It found that following up with these children is essential, yet this practice isn't done routinely across the UK, even though it was recommended in 2017. By creating a guide for doctors, the goal is to make sure that children get the support they need for their growth and learning, which can lead to better long-term outcomes. Who this helps: This helps children at risk of developmental problems and their families.

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This study looked at how using digital media, like social media and video games, affects the health and development of children and teenagers aged 0 to 18. It found that social media use is linked to increased rates of depression, substance use, and poorer academic performance, while video gaming is associated with higher aggression and some attention issues. Overall, more digital media use can pose risks to young people's well-being, making it important for families and policymakers to create strategies to reduce these potential harms. Who this helps: This research benefits parents, educators, and policymakers focused on child and adolescent health.

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This study focused on improving mental health services by addressing the social and economic needs of people with mental health issues. Researchers held workshops with healthcare professionals and experts to create a detailed plan, called a "Theory of Change," outlining six important steps needed to make sure that mental health care helps individuals feel valued and capable of thriving. These steps include providing culturally appropriate care and creating local support hubs, which can be adapted to enhance mental health services across the UK. Who this helps: This benefits patients with mental health conditions who need more supportive services.

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This study looked at how the COVID-19 pandemic affected the diagnosis and treatment of non-small cell lung cancer in the U.S. from 2014 to 2022. Researchers found that the percentage of patients diagnosed at an early stage increased slightly from 44% to 46%, but the time it took to start treatment went up by about 9 days overall. This delay was particularly pronounced in community cancer programs and affected Black patients the most, who waited an average of 56 days for treatment compared to 51 days for White patients. Who this helps: This research benefits patients, particularly those with lung cancer, by highlighting the importance of timely treatment.

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This study traced the collapse of eelgrass meadows in eastern James Bay, Canada, a coastal habitat critical to the Cree (Eeyou) people and migratory geese. Hydroelectric dam construction between 1978 and 1996 was identified as the primary cause, with climate-driven extreme events compounding the damage after 1998. The eelgrass has not recovered, and the Cree have had to adapt their traditional relationship with the coast.

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Researchers studied how the human immune system reacts to a pig kidney transplant in a brain-dead human. They found that specific immune cells in the blood increased significantly, leading to rejection of the kidney by day 33 after the transplant. This research is important because it helps identify ways to improve the success of pig organ transplants in humans, potentially addressing the shortage of available human organs for transplantation.

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This study looked at whether the Supreme Court's Dobbs decision in June 2022 led to an increase in suicides among women aged 15 to 49 in the U.S. The researchers found that there were about 104 additional suicides among this group after the decision, with the increase being especially significant among younger women aged 15 to 24, who saw about 78 extra suicides. These findings show that the Dobbs ruling has had a negative effect on the mental health of reproductive-aged women, highlighting the need for better support during such challenging times. Who this helps: This helps reproductive-aged women who may be struggling with mental health issues.

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This study explored ways to use implementation science to improve suicide prevention strategies. Experts from various backgrounds evaluated a set of statements and reached a consensus on 82 out of 90 proposed strategies, emphasizing the need for better research, resource allocation, and engaging those with lived experiences in the process. This is important because it can lead to more effective and evidence-based programs that reduce suicide rates. Who this helps: This helps patients at risk of suicide and the professionals who support them.

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This study focused on a unique case of an 8-year-old girl who developed compartment syndrome in her forearm after a fracture. She showed symptoms such as severe pain and bent fingers two weeks after her injury, which were treated with surgery, leading to improvement in her condition. While she had a successful recovery overall, she still experiences some sensory issues in her hand after six months. Who this helps: This research benefits doctors and healthcare providers working with pediatric patients to improve diagnosis and treatment of compartment syndrome.

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This study looked at specific proteins called myosins, which are important for the formation of small finger-like structures called filopodia in cells. Researchers found that a mutation in these myosins reduced the number and intensity of filopodia formed, with Myo10 showing a 40% decrease in movement speed within these structures, although it didn’t consistently change their length. Understanding how myosins work is crucial because it sheds light on the early steps of cell movement and communication, which could have implications for various diseases. Who this helps: This helps researchers and doctors studying cell behavior and potential treatments for diseases involving cell movement.

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This research examined a new urine test called Urine-ID™ to identify bacteria causing urinary tract infections (UTIs) in older patients who were not helped by standard tests. The study found that 92.86% of urine samples from patients showed at least one type of bacteria using the new test, compared to only 50% detection with the standard method, which missed 19.64% of infections. This matters because using the Urine-ID™ test can lead to quicker and more accurate treatments for UTIs, potentially improving patient recovery and reducing complications. Who this helps: Patients with complicated urinary tract infections.

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This study looked at the complications that occurred during or after collecting cerebrospinal fluid (CSF) from 11 dogs with neurological issues at a specific veterinary hospital. Out of 7,545 CSF collections, only 11 dogs (0.15%) had major complications, but unfortunately, 8 of these dogs were euthanized due to severe health failures afterward. Notably, many of the dogs showed signs of brain swelling and altered mental states before the procedure, indicating a higher risk for complications. Who this helps: This research benefits veterinarians and dog owners by highlighting the risks associated with CSF collection in dogs with neurological disorders.

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In 2024, researchers conducted a survey to check public opinion about the possibility of civil war in the United States. They found that only 6.5% believed a civil war was likely, and just 3.6% thought it was necessary to fix the country. Interestingly, of the small group who considered participating in a civil war, many were open to changing their minds if family, friends, or community leaders talked them out of it, showing a potential way to prevent conflict. Who this helps: This helps communities and leaders working to reduce political violence and promote peaceful dialogue.

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This study examined how certain chemical probing agents used in RNA research interact with proteins that bind to RNA. The researchers found that these chemicals not only target RNA but also modify specific amino acids in proteins, disrupting how proteins bind to RNA. This is important because understanding these interactions helps scientists develop better methods to study RNA and find new treatments for diseases linked to RNA-protein relationships. Who this helps: This benefits researchers and drug developers working on RNA-related illnesses.

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Researchers studied a group of mice with weakened immune systems to understand the outbreaks of a disease caused by a bacteria called Clostridioides cuniculi. They found that this bacteria led to mild symptoms like loose stools without significant weight loss or death, and it was linked to dirty bedding from affected mice. Treating the infected mice with a certain medication, trimethoprim-sulfamethoxazole, effectively cleared up the symptoms and the bacterial infection. Who this helps: This research benefits scientists and veterinarians working with immunodeficient mouse models in laboratories.

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This study looked at how certain programs aimed at improving social and economic conditions can help people with mental health issues, particularly those from marginalized communities. Researchers reviewed 78 papers and found that these targeted interventions were effective for different groups, including 50 individuals experiencing homelessness and 9 with a history of offending. This is important because addressing the integrated social and economic challenges these groups face can significantly enhance their mental health care and support their overall well-being. Who this helps: This helps patients with mental health issues from marginalized communities.

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This study looked at a condition called occult tethered cord syndrome (OTCS) in dogs, analyzing the symptoms, MRI results, and outcomes of treatment in 30 dogs. The researchers found that many dogs showed signs like pain in the lower back (97% reported), difficulty walking (70%), and some had neurological issues (90%). Importantly, surgery led to full recovery for many dogs, while those treated with medication often had poor results if they had higher severity scores or other complications. Who this helps: This benefits dogs diagnosed with OTCS and their veterinarians seeking better treatment options.

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This study looks at long noncoding RNAs (lncRNAs), which are important for controlling how cells work and can contribute to diseases when they don't function properly. Researchers examined how these lncRNAs are structured and how they interact with proteins, finding specific parts of them that could be targeted with new drugs. By focusing on well-known lncRNAs like MALAT1 and HOTAIR, the study highlights potential new treatments that could help manage diseases linked to these molecules. Who this helps: This benefits patients suffering from diseases related to lncRNA dysfunction.

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This study looked at how people in England, Scotland, and Wales feel about the police, surveying over 1,400 people. It found that many do not believe the police are meeting the standards expected of them, with only a few feeling confident in their legitimacy. The results showed that while overall trust is low, people feel slightly better about police visibility compared to fairness and proportionality, which are key to building trust. Who this helps: This benefits community members and policymakers working to improve police-community relationships.

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This study looked at how prisons can better support women who wish to breastfeed after giving birth. Researchers found three main things that help these programs succeed: clear protocols, supportive partnerships, and customized care for women’s needs. However, they also faced challenges like a lack of support within the prison system and unclear responsibilities for staff. Improving lactation support in prisons is essential because it benefits the health of both mothers and their babies. Who this helps: This helps incarcerated women who are new mothers.

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This study looked at a new device called TissueStat, designed to help doctors close wounds during minimally invasive spine surgeries. It was found that using TissueStat was faster (average of 2 minutes and 1 second compared to 3 minutes and 22 seconds for traditional sutures) and more accurate (0.22 mm off target vs. 1.25 mm for traditional sutures). This matters because better closing techniques can lead to fewer complications and happier patients. Who this helps: This helps patients undergoing spine surgery by reducing the risk of complications.

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This study focused on how health care professionals can effectively use digital tools while maintaining compassionate care. Researchers worked with 54 experts to identify key skills and technology features that promote compassion in digital health settings, resulting in a framework of 58 skills and 15 technology attributes. This matters because it helps ensure that as healthcare becomes more digital, it remains focused on patient care and empathy. Who this helps: This benefits health care professionals, patients, and organizations looking to improve digital health interactions.

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This study looked at how robotic-assisted surgery for lung cancer is being used across the United States from 2010 to 2021. Researchers found that the number of robotic surgeries surpassed the traditional video-assisted surgeries by 2019, with 9,579 robotic surgeries compared to 9,454 video-assisted ones. By 2021, robotic surgeries made up over 65% of all minimally invasive lung cancer surgeries, especially rising faster in academic hospitals and major cities compared to smaller community hospitals and rural areas. Who this helps: This benefits lung cancer patients by providing more access to advanced surgical options.

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Researchers found a new virus called EvenBluerMoon in the topsoil of Lubbock, Texas. This virus mainly attacks bacteria and has a unique structure with a round head and a long tail. Understanding such viruses is important because they can help in developing treatments for bacterial infections and improving soil health. Who this helps: This helps patients and doctors looking for new ways to treat bacterial infections.

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This study looked at how effective social programs are for people with mental health issues, especially those who face social and economic disadvantages. Researchers found that out of 266 studies, only 8% provided detailed information about how well these programs worked for different groups, such as by gender or socioeconomic status. The findings showed that interventions were less effective for those in lower socioeconomic groups. Who this helps: This research benefits patients with mental health challenges, especially those from marginalized communities.

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This study investigates how well crisis lines support Public Safety Personnel (PSP) in Canada, who face high rates of mental health challenges. Researchers are collecting information from PSP through surveys, interviews, and focus groups to understand their needs and the barriers they encounter when trying to access help. By the end of 2025, the findings will be used to create better recommendations for crisis line services, aiming to ensure that PSP receive effective and accessible mental health support. Who this helps: This benefits Public Safety Personnel and the organizations that support them.

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This study looks at how Canadians experienced thoughts of suicide during the COVID-19 pandemic. Researchers found that while the number of actual suicides remained about the same or even decreased, the number of people who thought about suicide doubled and more people attempted suicide. Understanding these experiences is important because it helps identify what support is needed for mental health during crises. Who this helps: This helps patients struggling with suicidal thoughts and mental health providers supporting them.

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Researchers studied a new DNA sequencing technology called Constellation to improve the diagnosis of rare diseases. They tested this method on DNA from 21 families and found that it accurately identified all known genetic variants causing their conditions and solved cases that were previously unresolved. This is important because it enhances the ability to detect complex genetic mutations, making diagnoses faster and more accessible. Who this helps: This benefits patients with rare diseases and their doctors.

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The study looked at how certain life events impact people's views on political violence in the U.S. over a year. Researchers found that 19.9% of respondents showed decreased support for political violence, while 14.2% showed increased support; for many, views stayed the same. Significant findings included that financial improvements led to decreased support for political violence, while giving up on politics increased support. Who this helps: This benefits policymakers and organizations focused on reducing political violence.

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This study looked at how different factors affected how long patients stayed in a special care unit before and during the COVID-19 pandemic. Researchers found that legal issues increased the length of stay by about 46%, and older patients tended to stay longer, with their length of stay increasing slightly each year. Overall, there were improvements over time in how quickly patients could be discharged, possibly due to lessons learned during the pandemic. Who this helps: This information is useful for healthcare providers and hospital administrators working to improve patient care and discharge processes.

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This study looked at 15 trauma databases worldwide to understand how well they collect and share information about injuries and treatments. The researchers found that while trauma patients often experience significant long-term issues, such as impairment even 6 to 12 months post-injury, data collection is mostly focused on survival rates, which limits the overall understanding of patient outcomes. They highlighted the need for standardized methods to improve data quality and better measure the success of trauma care, which could lead to improved treatment for patients. Who this helps: This helps trauma patients and healthcare providers.

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This study looked at patients who had minimally invasive lung surgeries and how many of them continued using opioids for pain relief after surgery. Out of 376 patients, 16.5% were still using opioids 30 days after the operation, 10.1% at 60 days, and 8.5% at 90 days. Higher amounts of opioids taken before leaving the hospital were linked to a greater chance of ongoing use; specifically, for every 10 additional milligrams of opioids, the likelihood of continued usage increased by about 21% at 30 days post-surgery. Who this helps: This research benefits patients recovering from lung surgery by highlighting the risks of prolonged opioid use.