Dr. Ronen studies how artificial intelligence can aid medical education by comparing its performance to that of human doctors in anesthesiology exams. He also investigates the release and movement of harmful chemicals, including PFAS (which can contaminate water supplies), and works on improving air quality monitoring through low-cost sensors. Additionally, Dr. Ronen is involved in research that examines medical practices such as anesthesia use during surgeries and the effectiveness of various interventions to enhance patient safety and outcomes.
Key findings
AI models like Claude 3.7 Sonnet and ChatGPT-4 scored 73.67% and 62.77% respectively on anesthesiology exams, compared to the best human score of 78.05%.
PFAS can be released from biosolid-derived compost within an hour, showing potential risks for water quality and public health.
The Deliberate Compensated Vasoplegia protocol reduced severe high blood pressure incidents during pheochromocytoma surgery from nearly 2 events per hour to just 0.03 events.
A new sensor for detecting PFOS in groundwater can identify levels as low as 25.2 parts per billion (ppb), providing a rapid and efficient detection method.
Neuraxial anesthesia usage during elective cesarean deliveries increased from 44.8% before the COVID-19 pandemic to 79.3% during it.
Frequently asked questions
Does Dr. Ronen study the impact of AI in medicine?
Yes, he compares the performance of AI models against human doctors in medical exams to evaluate their potential role in education.
What environmental issues does Dr. Ronen address?
He researches the release of harmful chemicals like PFAS from compost and their effects on water safety and public health.
What treatments has Dr. Ronen researched in surgery?
He has investigated the use of tranexamic acid for reducing blood loss in bariatric surgery and the management of blood pressure during surgeries for tumors.
Is Dr. Ronen's work relevant for patients undergoing anesthesia?
Yes, his research on anesthesia practices and outcomes directly informs patient care in surgeries, especially cesarean deliveries.
How does Dr. Ronen contribute to air quality monitoring?
He studies improving the accuracy of low-cost sensors that detect air particles to better monitor air quality and its impact on health.
Publications in plain English
Multi-compound PFAS transport in the unsaturated zone during infiltration cycles.
2026
Water research
Kolade SO, Ronen A, Turkeltaub T, Tsakiroglou C, Klint KES +2 more
Plain English This study looked at how different types of PFAS, a group of harmful chemicals, move through soil during wet and dry cycles. Researchers found that short-chain PFAS move easily through the soil, while long-chain PFAS stay trapped for longer periods. This knowledge is important because it helps us understand how PFAS can spread in the environment and can inform better cleanup methods for contaminated areas.
Who this helps: This helps environmental scientists and policymakers working on pollution remediation.
Perfluoroalkyl and Polyfluoroalkyl Substances Release from Biosolid-Derived Compost.
2026
ACS omega
Huang X, Arye G, Zhang W, Ronen A
Plain English This study explored how certain chemical substances, known as PFAS, are released from compost made from treated sewage sludge. Researchers found that PFAS can be released quickly, with some types almost completely released in just an hour, while others take much longer, indicating that the way these substances behave depends on their chemical structure and the composition of the compost. This is significant because it helps us understand how PFAS can move from soil into the water supply, which is important for environmental safety and public health.
Who this helps: This helps patients and communities concerned about water quality and pollution.
Large language models versus human examinee performance on Israeli anesthesiology board examinations.
2026
Scientific reports
Ronen A, Fein S, Orbach-Zinger S, Heesen P, Shpack O +6 more
Plain English This study compared the performance of two advanced AI models, Claude 3.7 Sonnet and ChatGPT-4, with human doctors taking the Israeli anesthesiology board exams, which consisted of 450 multiple-choice questions. Claude scored 73.67%, outperforming human examinees who averaged 62.77%, but both AIs still fell short of the best human scores at 78.05%. The findings are important because they show that while AI can be a useful tool in evaluating medical knowledge, it has inconsistent performance based on question type and doesn’t yet match the top human exam takers.
Who this helps: This research benefits patients and doctors by informing how AI can support medical education and assessment.
The Effect of Preoperative Single-Dose Tranexamic Acid on Bleeding and Thromboembolic Events Following Bariatric Surgery.
2025
Obesity surgery
Lourie NEE, Kupietzky A, Maden A, Sharvit S, Ronen A +5 more
Plain English This study looked at whether giving patients a single dose of tranexamic acid (TXA) before bariatric surgery can help reduce bleeding and related complications. Researchers analyzed data from 901 patients and found that TXA did not significantly lower blood loss, transfusion needs, or other issues like blood clots after surgery. This is important because it indicates that TXA may not be effective in preventing bleeding in these patients, so more research is needed to determine the best ways to manage this risk.
Who this helps: This helps doctors and patients preparing for bariatric surgery.
Interfacial Heating in Membrane Distillation: Advances, Optimization Strategies, and Industrial Applications for Desalination.
2025
Environmental science & technology
Hu J, Zhu G, Ronen A, Jassby D, Li Q +3 more
Plain English This study looked at a new method called interfacial heating membrane distillation (IH-MD), which uses targeted heating to improve the process of turning salty water into fresh drinking water. The researchers found that while IH-MD can effectively reduce energy use and maintain stable performance, challenges like material wear and system complexity need to be addressed for it to work in real-world settings. This is important because IH-MD has the potential to make water purification more efficient and sustainable, especially when combined with renewable energy sources.
Who this helps: This benefits water treatment facilities and communities facing water scarcity.
Detection of perfluorooctance sulphonic acid in groundwater using an intelligent array of electrochemical sensors.
2025
Journal of hazardous materials
Khadka M, Pasternak YM, Sheinenzon O, Snezhko A, Ronen A +2 more
Plain English This research focused on creating a new type of sensor to quickly detect a harmful chemical called perfluorooctane sulfonic acid (PFOS) in groundwater. The sensor is made from special materials that react with PFOS, allowing it to identify its presence at levels as low as 25.2 parts per billion (ppb). This is important because current detection methods are slow and require expensive lab equipment, so having a quick and easy way to test water can help protect public health and the environment.
Who this helps: This benefits public health officials and environmental scientists monitoring water safety.
Visibility-Based Calibration of Low-Cost Particulate Matter Sensors: Laboratory Evaluation and Theoretical Analysis.
2025
Sensors (Basel, Switzerland)
Ronen A
Plain English This study focused on improving the accuracy of inexpensive sensors used to detect tiny particles in the air, which can impact health. Researchers tested a new calibration method using visibility sensors that track how light is affected by these particles. They found that by adjusting the readings of the low-cost sensors based on atmospheric conditions, the accuracy was greatly improved, making it possible to use these sensors effectively in various settings, even where resources are limited.
Who this helps: This benefits patients and communities by improving air quality monitoring, potentially leading to better health outcomes.
Deliberate Compensated Vasoplegia-A Novel Pharmaceutical Approach for Controlling Blood Pressure During Surgery for Pheochromocytoma.
2023
World journal of surgery
Mazeh H, Weiss D, Peter M, Grozinsky-Glasberg S, Oleinikov K +3 more
Plain English This study looked at a new approach to managing blood pressure during surgery for a type of tumor called pheochromocytoma. Researchers found that using the Deliberate Compensated Vasoplegia (DCV) protocol led to a significant drop in severe high blood pressure incidents during surgery, going from nearly 2 events per hour to just 0.03 events per hour. This is important because controlling blood pressure can prevent complications during surgery and improve patient safety.
Who this helps: Patients undergoing surgery for pheochromocytoma.
A Review on Removal and Destruction of Per- and Polyfluoroalkyl Substances (PFAS) by Novel Membranes.
2022
Membranes
Das S, Ronen A
Plain English This research paper reviewed new methods for removing and destroying harmful chemicals known as PFAS, which have been used in many everyday products since the 1940s. PFAS are tough to break down and can lead to serious health problems like cancer and hormonal issues. The study highlighted various new membrane techniques that show promise in effectively separating and eliminating PFAS, discussing their performance and cost, and offering insights on future advancements in treatment methods.
Who this helps: This benefits patients and communities affected by PFAS contamination.
Enhanced Separation Performance of Hierarchically Porous Membranes Fabricated via the Combination of Crystallization Template and Foaming.
2022
Polymers
Shi J, Zhou J, Fan D, Lin T, Wang J +4 more
Plain English This study focused on creating new porous membranes made from a special plastic called poly(vinylidene fluoride) (PVDF) by using a mix of techniques. The researchers found that by using a chemical foaming agent, they could produce membranes that had significantly better performance in allowing substances to pass through: these membranes achieved up to 20 times more fluid flow without sacrificing their ability to filter out unwanted materials. This improvement is important because it can lead to more efficient filtration processes in various applications, such as water purification and chemical separations.
Who this helps: This benefits industries that rely on efficient filtration, including water treatment facilities and chemical manufacturers.
Investigation of the protection efficacy of face shields against aerosol cough droplets.
2021
Journal of occupational and environmental hygiene
Ronen A, Rotter H, Elisha S, Sevilia S, Parizer B +2 more
Plain English This study examined how effective face shields are at blocking cough droplets compared to regular surgical masks during the COVID-19 pandemic. The researchers found that face shields blocked larger droplets (over 3 micrometers) just as well as masks and were even better at blocking smaller particles, stopping about ten times more particles than masks. However, the effectiveness of the shield depended on its shape, with wider shields performing better.
Who this helps: This research benefits patients and healthcare workers by informing them about protective equipment options.
Reactive electrically conducting membranes for phosphorus recovery from livestock wastewater effluents.
2021
Journal of environmental management
Kekre KM, Anvari A, Kahn K, Yao Y, Ronen A
Plain English This study looked at a new way to filter livestock wastewater to recover valuable nutrients like nitrogen and phosphorus, which are turned into an eco-friendly fertilizer called struvite. The researchers found that their method was able to remove up to 65% of these nutrients within just 30 minutes, and it worked without the need for extra chemicals to manage acidity, making the process cheaper at about $158 for each ton of fertilizer produced. This is important because it provides a more efficient and cost-effective method for managing livestock waste while producing a useful product and clean water.
Who this helps: This helps farmers and agricultural industries looking for sustainable waste management solutions.
Sensing with Polarized LIDAR in Degraded Visibility Conditions Due to Fog and Low Clouds.
2021
Sensors (Basel, Switzerland)
Ronen A, Agassi E, Yaron O
Plain English This study examined how LIDAR sensors, which help autonomous vehicles navigate, perform in foggy and cloudy weather. The researchers found that using polarization techniques can improve LIDAR performance in these low visibility conditions, recovering some of the signal loss. This is important because it could make self-driving technology safer and more reliable in various weather conditions.
Who this helps: This helps developers of autonomous vehicles and the safety of drivers and passengers.
A Retrospective Investigation of Neuraxial Anesthesia Rates for Elective Cesarean Delivery Before and During the SARS-CoV-2 Pandemic.
2021
The Israel Medical Association journal : IMAJ
Binyamin Y, Heesen P, Gruzman I, Zlotnik A, Ioscovich A +5 more
Plain English This study looked at how often women received neuraxial anesthesia, like epidurals, during elective cesarean deliveries before and during the COVID-19 pandemic. Researchers found that the use of neuraxial anesthesia increased significantly from 44.8% before the pandemic to 79.3% during it, showing that education and support helped change patient choices. This is important because neuraxial anesthesia is often safer and leads to better recovery for mothers compared to general anesthesia.
Who this helps: This benefits patients undergoing cesarean deliveries.
The effect of preoperative anxiety on phenylephrine dose during cesarean delivery: An open controlled one-arm clinical trial.
2020
Acta anaesthesiologica Scandinavica
Danon E, Heesen P, Orbach-Zinger S, Kornilov E, Ronen A +2 more
Plain English This study looked at whether anxiety before surgery affects the amount of phenylephrine needed to keep blood pressure stable during a cesarean delivery under spinal anesthesia. Researchers involved 94 women and found that preoperative anxiety did not significantly change the amount of phenylephrine used, with a correlation score of just 0.05. This is important because it suggests that other factors, not just anxiety, play a role in managing blood pressure during this type of surgery.
Who this helps: This helps doctors involved in cesarean deliveries by providing clarity on the influence of anxiety on medication dosages.
The association between hand grip strength and rehabilitation outcome in post-acute hip fractured patients.
2019
Aging clinical and experimental research
Hershkovitz A, Yichayaou B, Ronen A, Maydan G, Kornyukov N +2 more
Plain English This study looked at how hand grip strength affects the recovery of patients who recently had hip fractures. Among 373 patients, those with stronger hand grips had a better chance of improving their mobility after rehabilitation, with a 6.4% greater likelihood of achieving significant recovery. Higher grip strength was important for better functional outcomes, which means stronger patients tend to regain independence faster.
Who this helps: This research benefits patients recovering from hip fractures and their doctors by identifying those who may need more support in rehab.
Low voltage electric potential as a driving force to hinder biofouling in self-supporting carbon nanotube membranes.
2018
Water research
Thamaraiselvan C, Ronen A, Lerman S, Balaish M, Ein-Eli Y +1 more
Plain English This study explored how low voltage electric fields can stop bacteria from sticking to and damaging special membranes made from carbon nanotubes. Researchers found that using an alternating current (AC) at a voltage of 1.5 volts effectively prevented over 98.5% of bacterial attachment and inactivated about 95.3% of the bacteria during tests. These findings are significant because they suggest that using electric fields could improve the performance and maintenance of filtration systems, which is crucial for clean water and other applications.
Who this helps: This benefits researchers and engineers working on water treatment and filtration technologies.
Comparison of three different techniques for camera and motion control of a teleoperated robot.
2017
Applied ergonomics
Doisy G, Ronen A, Edan Y
Plain English This study looked at different ways to control a robot's movements and camera using the operator's head movements instead of traditional methods like joysticks. The researchers tested three techniques and found that using head orientation to control the camera can make it easier for new users to operate the robot, but it still needs more improvement to work as well as the classic joystick method. This is important because it could make robotic systems more user-friendly for people who are not experienced in using them.
Who this helps: This benefits operators and users of teleoperated robots, especially beginners.
Cognitive-behavioral versus non-directive therapy for preschoolers with severe nighttime fears and sleep-related problems.
2017
Sleep medicine
Kahn M, Ronen A, Apter A, Sadeh A
Plain English This study looked at how effective two types of therapy are for preschoolers aged four to six who have severe fears at night and problems sleeping. Ninety children participated, with those receiving cognitive-behavioral therapy that involved parents (CBT-PIP) showing greater improvement in reducing sleep problems and co-sleeping compared to a different therapy (TEPT). While both treatments helped reduce fears and improve sleep, parents reported that CBT-PIP was more effective in addressing behavioral issues related to nighttime fears.
Who this helps: This benefits parents and caregivers of preschoolers with severe nighttime fears and sleep issues.
[SEX DIFFERENCES IN PHYSIOLOGICAL RESPONSES TO PAIN THROUGHOUT SURGICAL PROCEDURES].
2017
Harefuah
Ronen A, Shochat T, Eidelman L
Plain English This research looked at how men and women react to pain during abdominal surgeries, specifically focusing on changes in heart rate and blood pressure. The study analyzed data from 50 patients (25 men and 25 women) undergoing surgery and found that there were no significant differences in how their heart rate and blood pressure responded to pain during the procedure. This is important because understanding these differences can help improve pain management strategies for different genders in surgical settings.
Who this helps: Patients undergoing surgery.
Polyaniline-Coated Carbon Nanotube Ultrafiltration Membranes: Enhanced Anodic Stability for In Situ Cleaning and Electro-Oxidation Processes.
2016
ACS applied materials & interfaces
Duan W, Ronen A, Walker S, Jassby D
Plain English This study looked at new membranes made from polyaniline and carbon nanotubes designed to filter water while also cleaning themselves. The researchers found that these membranes were about ten times more electrically conductive than previous versions and remained stable even under challenging conditions. They could also effectively clean themselves during use and could break down a harmful compound with 90% efficiency in one pass.
Who this helps: This benefits water treatment facilities and industries that need to purify water and remove contaminants effectively.
Preparation and use of varied natural tools for extractive foraging by bonobos (Pan Paniscus).
2015
American journal of physical anthropology
Roffman I, Savage-Rumbaugh S, Rubert-Pugh E, Stadler A, Ronen A +1 more
Plain English This study looked at how bonobos, a type of ape, use different tools to find food in both zoo and sanctuary settings. The researchers found that bonobos in the sanctuary were better at using tools for tasks, successfully retrieving hidden food using items like sticks and antlers, while the zoo bonobos showed less skill. This matters because it shows that bonobos can be really good at using tools, similar to chimpanzees, and may help us understand early human foraging techniques.
Who this helps: This helps researchers, animal caregivers, and those interested in primate behavior.
Microbial Attachment Inhibition through Low-Voltage Electrochemical Reactions on Electrically Conducting Membranes.
2015
Environmental science & technology
Ronen A, Duan W, Wheeldon I, Walker S, Jassby D
Plain English This study looked at how using low electrical voltages on special membranes can stop bacteria from sticking to surfaces in water treatment systems. Researchers found that applying a voltage of 1.5 volts helped kill up to 67% of bacteria, while at 1 volt, about 92% of the bacteria stayed alive. This matters because reducing bacterial attachment can lead to cleaner water and more effective filtration processes.
Who this helps: This benefits water treatment facilities and the communities that rely on clean water.
The combination of short rest and energy drink consumption as fatigue countermeasures during a prolonged drive of professional truck drivers.
2014
Journal of safety research
Ronen A, Oron-Gilad T, Gershon P
Plain English This study looked at how taking short breaks and drinking energy drinks can help professional truck drivers stay alert during long drives. Fifteen drivers participated in tests where they either drank a placebo, an energy drink with caffeine, or the energy drink followed by a 10-minute break. The results showed that those who consumed the energy drink had fewer issues with lane position and steering during the first 80-100 minutes of driving, and those who rested after 100 minutes maintained their focus better for the rest of the drive.
Who this helps: This information benefits truck drivers and their employers by providing strategies to combat fatigue on long trips.
Predetermined flake production at the Lower/Middle Paleolithic boundary: Yabrudian scraper-blank technology.
2014
PloS one
Shimelmitz R, Kuhn SL, Ronen A, Weinstein-Evron M
Plain English This study looked at stone tool-making techniques from a specific time period (around 415,000 to 320,000 years ago) in Tabun Cave. Researchers found that early humans planned their tool production in a way that was more organized than previously thought, even if it wasn't as complex as later methods. This finding shows that the shift in how we understand the development of tool-making from the Lower to the Middle Paleolithic may not be as clear-cut as once believed, revealing early innovations in how humans utilized stone tools.
Who this helps: This helps archaeologists and historians understand early human technology and behavior.
'Fire at will': the emergence of habitual fire use 350,000 years ago.
2014
Journal of human evolution
Shimelmitz R, Kuhn SL, Jelinek AJ, Ronen A, Clark AE +1 more
Plain English Researchers looked at how and when early humans started using fire regularly. They found that around 350,000 to 320,000 years ago, fire use became a common part of daily life for these early humans, which helped them adapt and survive in different environments. This shift is important because it shows how fire use influenced our evolution and social development.
Who this helps: This information benefits anthropologists and historians studying human evolution and social behavior.
Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity.
2013
Scientific reports
Shechter R, London A, Kuperman Y, Ronen A, Rolls A +2 more
Plain English This study looked at a receptor in the brain called TLR2 and its role in preventing weight gain as we age. Researchers found that mice lacking TLR2 became overweight as they got older and gained more weight on a high-fat diet. Specifically, these mice struggled with controlling their food intake, highlighting that TLR2 helps manage body weight and energy use.
Who this helps: This benefits patients at risk of obesity, especially as they age.
Vestibulo-ocular response and balance control in children and young adults with mild-to-moderate intellectual and developmental disability: a pilot study.
2013
Research in developmental disabilities
Zur O, Ronen A, Melzer I, Carmeli E
Plain English This study looked at how well children and young adults with mild-to-moderate intellectual and developmental disabilities (IDD) can control their eye movements and balance. Out of 21 participants, 62% (or 13 individuals) showed problems with their vestibulo-ocular response (VOR), which affects balance. Those who had a VOR deficit were able to maintain their balance for an average of 12 seconds while standing on foam with their eyes closed, compared to 29 seconds for those who did not have the deficit. This matters because testing VOR function can help identify balance issues early on, allowing for better support and interventions.
Who this helps: This helps patients with IDD and their caregivers.
Guardrail influence on pedestrian crossing behavior at roundabouts.
2013
Accident; analysis and prevention
Cohen A, Bar-Gera H, Parmet Y, Ronen A
Plain English The study looked at how guardrails influence where pedestrians choose to cross at roundabouts in Israel. Researchers observed over 11,000 crossings and found that nearly 25% of pedestrians crossed outside of designated crosswalks, mostly when no guardrail was present. Violations were 20-30% more common without guardrails, and more pedestrians followed the rules when traffic was heavier. This matters because improving the design of roundabouts with guardrails can help keep pedestrians safer.
Who this helps: This helps pedestrians and urban planners focused on improving road safety.
Impact of ZnO embedded feed spacer on biofilm development in membrane systems.
2013
Water research
Ronen A, Semiat R, Dosoretz CG
Plain English This study looked at how a special feed spacer containing zinc oxide nanoparticles can reduce biofilm growth on membranes used in water filtration systems. The researchers found that using these modified spacers led to at least a 50% reduction in the decrease of water flow through the membranes and fewer bacteria were found attached to them compared to regular spacers. This matters because it could improve the efficiency and longevity of water filtration systems by preventing clogging caused by bacterial growth.
Who this helps: This benefits water treatment facilities and their operators.
Immunomodulation by poly-YE reduces organophosphate-induced brain damage.
2012
Brain, behavior, and immunity
Finkelstein A, Kunis G, Berkutzki T, Ronen A, Krivoy A +12 more
Plain English This study looked at how a treatment called poly-YE can help reduce brain damage caused by exposure to harmful chemicals known as organophosphates. In tests on rats, giving a single injection of poly-YE after poisoning led to better survival of brain cells and less damage, with significant findings indicating that more brain-supporting cells and proteins were present afterward. These results matter because they provide a potential new way to treat brain injuries from organophosphate poisoning, which currently lacks effective therapies.
Who this helps: This helps patients affected by organophosphate poisoning, including agricultural workers and victims of chemical attacks.
The perception of pedestrians from the perspective of elderly experienced and experienced drivers.
2012
Accident; analysis and prevention
Bromberg S, Oron-Gilad T, Ronen A, Borowsky A, Parmet Y
Plain English This study looked at how well older drivers notice pedestrians when driving in residential areas. Researchers found that elderly drivers took longer to spot potential dangers and struggled with recognizing certain pedestrian events compared to more experienced drivers. For example, elderly drivers' response times were slower, and they drove about 20% slower than their counterparts, likely because they are aware of their challenges in hazard detection. This matters because better awareness of pedestrian-related risks can help improve safety for everyone on the road.
Who this helps: This helps elderly drivers and road safety organizations.
Stone tool production and utilization by bonobo-chimpanzees (Pan paniscus).
2012
Proceedings of the National Academy of Sciences of the United States of America
Roffman I, Savage-Rumbaugh S, Rubert-Pugh E, Ronen A, Nevo E
Plain English This study looked at how two bonobo-chimpanzees, Kanzi and Pan-Banisha, made and used stone tools. They created a greater variety of flint tools than what researchers previously observed, including tools for breaking logs and digging for food. For example, they used small flakes like drills and thicker flakes as axes, showing that these bonobos can use tools in complex ways similar to humans.
Who this helps: This research benefits scientists studying animal intelligence and the evolution of tool use.
Usage and perceived effectiveness of fatigue countermeasures for professional and nonprofessional drivers.
2011
Accident; analysis and prevention
Gershon P, Shinar D, Oron-Gilad T, Parmet Y, Ronen A
Plain English This study looked at how both professional and nonprofessional drivers manage fatigue while driving. Researchers surveyed 190 drivers, finding that both groups frequently use methods like listening to the radio and opening windows to stay alert. However, professional drivers also plan ahead for breaks and rely more on strategies like taking short naps and drinking coffee, which they find more effective than nonprofessional drivers do. This is important because understanding these coping strategies can help improve road safety, especially by encouraging better practices among nonprofessional drivers.
Who this helps: This helps drivers, especially nonprofessional ones, improve their alertness and safety on the road.
Vibrotactile "on-thigh" alerting system in the cockpit.
2011
Human factors
Salzer Y, Oron-Gilad T, Ronen A, Parmet Y
Plain English This study looked at using a device on pilots' thighs that vibrates to direct their attention in the cockpit during critical situations. The researchers found that a setup with four vibration points was more effective at guiding pilots accurately when they needed to escape from danger. This is important because it may help pilots respond better in emergencies by enhancing their awareness of their environment without distracting them from other visual or auditory alerts.
Who this helps: This helps pilots by improving their ability to react quickly and safely in high-pressure situations.
Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS.
2011
PloS one
Finkelstein A, Kunis G, Seksenyan A, Ronen A, Berkutzki T +3 more
Plain English This study looked at how certain immune cells called NKT cells change in a mouse model of amyotrophic lateral sclerosis (ALS), a severe disease that affects nerve cells and leads to muscle weakness. The researchers found that NKT cells were much higher in number in the sick mice, especially in the liver, where they noticed significant changes in other factors like insulin-like growth factor levels. By adjusting these NKT cells using a specific treatment, the scientists were able to slightly extend the life of the mice, highlighting that immune responses and liver health are important in ALS.
Who this helps: This research benefits patients with ALS by identifying new potential treatment targets.
The effect of alcohol, THC and their combination on perceived effects, willingness to drive and performance of driving and non-driving tasks.
2010
Accident; analysis and prevention
Ronen A, Chassidim HS, Gershon P, Parmet Y, Rabinovich A +3 more
Plain English The study examined how alcohol (0.05% blood alcohol concentration), THC (13 mg), and their combination affect driving abilities and people's willingness to drive. Researchers found that using both alcohol and THC together seriously impaired performance on driving and other tasks, leading to noticeable effects on mood and physical responses, such as heart rate. However, despite experiencing varying effects from the substances, participants remained equally willing to drive regardless of how impaired they felt.
Who this helps: This research benefits both patients who use these substances and the doctors advising them on the risks of driving under their influence.
Autoimmune spread to myelin is associated with experimental autoimmune encephalomyelitis induced by a neuronal protein, beta-synuclein.
2009
Journal of neuroimmunology
Kela-Madar N, de Rosbo NK, Ronen A, Mor F, Ben-Nun A
Plain English This study looked at how the immune system attacks a protein called beta-synuclein in the brains of rats, which can lead to a condition similar to multiple sclerosis (MS). Researchers found that specific immune cells that target beta-synuclein also start attacking myelin (the protective covering of nerves), which could contribute to nerve damage. They discovered that these attacking cells respond not just to beta-synuclein but also to other nerve components, highlighting a connection between autoimmunity and damage to myelin.
Who this helps: This research benefits patients with multiple sclerosis and their doctors by providing insight into how the disease might develop and progress.
Evaluation of experience-based fatigue countermeasures.
2009
Accident; analysis and prevention
Gershon P, Shinar D, Ronen A
Plain English This study looked at how different methods can help drivers stay alert and avoid fatigue while driving. Researchers tested an energy drink and the activity of shelling and eating sunflower seeds on twenty participants during a two-hour driving simulation. They found that both the energy drink and the sunflower seed activity significantly helped reduce feelings of fatigue, but while the energy drink improved driving performance, the seed activity made it harder to control the vehicle.
Who this helps: This helps drivers who struggle with fatigue on long trips.
Plain English This study looked at how certain tasks, called alertness maintaining tasks (AMTs), affect driving performance and alertness, particularly during long, monotonous driving. Among the tasks tested, the trivia AMT was the most effective, helping drivers avoid performance decline and increasing their alert feelings, while other tasks either made them feel sleepier or adversely affected their driving speed. This is important because it shows that engaging drivers with certain activities could improve safety on the road during tiring drives.
Who this helps: This helps professional truck drivers by enhancing their alertness and performance while driving.
Effects of THC on driving performance, physiological state and subjective feelings relative to alcohol.
2008
Accident; analysis and prevention
Ronen A, Gershon P, Drobiner H, Rabinovich A, Bar-Hamburger R +3 more
Plain English This study examined how different amounts of THC, the active ingredient in marijuana, affect driving performance, physical health, and feelings compared to alcohol. It found that both low THC and moderate alcohol intake negatively impacted driving skills, but THC made drivers feel more physically strained and uncomfortable, while alcohol made them sleepier. Notably, after using THC, participants drove slower, whereas they drove faster after drinking alcohol, but there were no lingering effects of THC after 24 hours.
Who this helps: This research helps patients and drivers understand the risks of using THC and alcohol before driving.
Shechter R, Ronen A, Rolls A, London A, Bakalash S +2 more
Plain English This study looked at how a protein called Toll-like receptor 4 (TLR4) affects the growth of retinal progenitor cells (RPCs) in the eye. Researchers found that mice without TLR4 had more RPC growth shortly after birth, suggesting that TLR4 normally limits this growth. Specifically, they noted that increased TLR4 presence was linked to stopping RPC growth, which is important because understanding this process could help develop treatments for retinal diseases.
Who this helps: This research benefits patients with retinal diseases and doctors treating vision disorders.
Rolls A, Shechter R, London A, Ziv Y, Ronen A +2 more
Plain English This study looked at how certain receptors, called Toll-like receptors (TLRs), influence the growth of new neurons in the adult brain's hippocampus, which is important for learning and memory. Researchers found that TLR2 and TLR4 play different roles: mice without TLR2 had fewer new neurons, while those lacking TLR4 produced more. Understanding these mechanisms is crucial because it could lead to new ways to promote brain health and recovery from neural damage.
Who this helps: This helps patients with brain injuries or neurodegenerative diseases.
Road characteristics and driver fatigue: a simulator study.
2007
Traffic injury prevention
Oron-Gilad T, Ronen A
Plain English This study looked at how different types of roads affect driver fatigue during long simulator driving sessions. The researchers found that on straight roads, drivers tended to drive faster and had more issues with staying in their lanes, while on winding roads, they also drove faster but focused more on steering. This is important because understanding how road conditions lead to fatigue can help improve road safety and driver performance.
Who this helps: This benefits drivers and road safety planners.
Description of an as yet unclassified DNA virus from diseased Cyprinus carpio species.
2005
Journal of virology
Hutoran M, Ronen A, Perelberg A, Ilouze M, Dishon A +3 more
Plain English Researchers studied a new DNA virus that is making koi and common carp sick, leading to high death rates – between 75% to 95% – and significant financial losses for fish farmers in Israel. The virus causes symptoms like fatigue and difficulty breathing in the fish and can lead to other health issues, confirming its role as the main cause of these deaths. This discovery is important because it helps identify the specific virus responsible, which could lead to better management and prevention strategies for affected fish populations.
Who this helps: This helps fish farmers and aquaculture practitioners.
Protection of cultured Cyprinus carpio against a lethal viral disease by an attenuated virus vaccine.
2005
Vaccine
Perelberg A, Ronen A, Hutoran M, Smith Y, Kotler M
Plain English This study looked at how to protect koi and common carp from a deadly viral disease caused by the koi herpes virus (KHV). Researchers found that by using a weakened version of the virus, they can create a vaccine to keep the fish safe. They demonstrated that immersing the fish in this vaccine works well, and they also discovered that keeping the fish at certain temperatures can affect how the virus spreads, which is crucial for developing an effective vaccination strategy.
Who this helps: This helps fish farmers and the aquaculture industry by reducing fish loss and improving economic stability.
Flint mining in prehistory recorded by in situ-produced cosmogenic 10Be.
2004
Proceedings of the National Academy of Sciences of the United States of America
Verri G, Barkai R, Bordeanu C, Gopher A, Hass M +7 more
Plain English This study looked at how ancient people mined flint to make tools, focusing on two sites in Israel. Researchers found that flint artifacts from Qesem Cave were likely collected from the surface or shallow areas, while those from Tabun Cave came from deeper layers, indicating that early humans were actively mining for flint. This finding helps us understand the technological advancements and resource management of our ancestors.
Who this helps: This helps archaeologists and historians studying human evolution and early technology.
Pathogenesis of acute viral disease induced in fish by carp interstitial nephritis and gill necrosis virus.
2004
Journal of virology
Pikarsky E, Ronen A, Abramowitz J, Levavi-Sivan B, Hutoran M +5 more
Plain English This study focused on a deadly virus that affects koi and common carp, causing significant health issues and financial losses for fish farms since 1998. Researchers discovered that the virus can kill 85 to 100% of infected fish within 7 to 21 days and found it primarily targets the kidneys, with notable damage also occurring in the gills. Understanding this virus helps fish farmers better manage and prevent outbreaks, ultimately protecting their fish and livelihoods.
Who this helps: This helps fish farmers and aquaculture businesses.
Efficient vaccine against the virus causing a lethal disease in cultured Cyprinus carpio.
2003
Vaccine
Ronen A, Perelberg A, Abramowitz J, Hutoran M, Tinman S +3 more
Plain English Researchers studied a virus that causes severe disease in ornamental Koi and Common carps, which can lead to high mortality rates in these fish. They found that carps exposed to the virus and then moved to a warmer temperature developed strong immunity, producing high levels of virus-fighting antibodies. By creating a safer version of the virus as a vaccine, they can protect these fish from the disease, which is important for the health of carp fisheries worldwide.
Who this helps: This helps fish farmers and the ornamental fish industry.